Electrochemical reduction of 2,2-dibromoacetophenone

摘要

The cathodic reduction of 2,2-dibromoacetophenone in aprotic medium DMF-LiClO4 yields (E)-4,4-dibromo-1,3-diphenyl-2,3-epoxybutan-1-one as the major product and trans-1,2,3-tribenzoylcyclopropane through an ionic or carbene route, respectively. When the electrolysis is carried out under highly dilute conditions, together with these products, (E)-4-bromo-1,3-diphenyl-2,3-epoxybutan-1-one and (Z)-4-bromo-1,3-diphenyl-2,3-epoxybutan-1-one are obtained. [References: 6]