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Tolerance of fragranced and fragrance-free facial cleansers in adults with clinically sensitive skin.

机译:成人对临床敏感皮肤的芳香型和无香型洁面乳的耐受性。

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Although mild, fragrance-free, nonfoaming cleansers generally are recommended for individuals with sensitive skin, many consumers choose fragranced foaming cleansers. The addition of hydrophobically modified polymers (HMPs) to mild facial cleansers has been shown to improve product tolerability in individuals with sensitive skin while facilitating foaming. The objective of the 2 studies reported here was to assess the tolerability of a mild, HMP-containing, foaming facial cleanser with a fragrance that was free of common allergens and irritating essential oils in patients with sensitive skin. In the first study, 8 participants with clinically diagnosed fragrance sensitivity used a gentle foaming HMP-containing facial cleanser with or without fragrance for 3 weeks. Both cleansers improved global disease severity, irritation, and erythema with similar cleansing effectiveness. The second study was a 3-week, prospective, double-blind, randomized, 2-center study of 153 participants with clinically diagnosed sensitive skin. In this study, the fragranced gentle foaming cleanser with HMP was as well tolerated as a benchmark gentle, fragrance-free, nonfoaming cleanser. Itching, irritation, and desquamation were most improved from baseline in both groups. The participant-rated effectiveness of the cleanser with HMP was similar or better than the benchmark cleanser after 3 weeks of use. In conclusion, the gentle facial cleanser with HMPs and a fragrance offers a new option for adults with sensitive skin who may prefer, and commonly use, a fragranced and foaming product.
机译:尽管通常建议皮肤敏感的人使用温和,无香,无泡沫的清洁剂,但许多消费者还是选择加香的泡沫清洁剂。已显示在温和的洗面奶中添加疏水改性聚合物(HMP)可以改善敏感皮肤个体的产品耐受性,同时促进起泡。此处报道的两项研究的目的是评估敏感性皮肤患者中不含HMP的温和泡沫洁面乳与不含常见过敏原和刺激性精油的芳香剂的耐受性。在第一项研究中,有8位经临床诊断出对香水敏感的参与者使用了含或不含香水的温和发泡的含HMP的洗面奶3周。两种清洁剂均具有相似的清洁效果,从而改善了整体疾病的严重程度,刺激性和红斑。第二项研究是一项为期3周,前瞻性,双盲,随机,2中心研究,共153名临床诊断为敏感皮肤的参与者。在这项研究中,具有HMP香气的柔和泡沫清洁剂与基准温和,无香,无泡沫的清洁剂一样具有良好的耐受性。两组的瘙痒,刺激和脱皮症状均较基线改善最大。使用HMP的清洁剂使用3周后,其参与者评估的有效性与基准清洁剂相似或更好。总之,温和的带有HMPs和香精的洗面奶为敏感肌肤的成年人提供了新的选择,他们可能更喜欢并通常使用带有香气和泡沫的产品。

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