Jejunal Gastrointestinal Stromal Tumours Presenting as Common Abdominal Symptoms and a Review of the Literature

摘要

Gastrointestinal stromal tumours (GISTs) are rare representing 0.1-3% of all gastrointestinal malignancies. They are mesenchymal tumours whose behaviour is driven by mutations in the tryrosin kinase receptor c-KIT. We report two jejunal GISTs presenting as common abdominal problems along with a review of the literature. Gastrointestinal stromal tumours (GISTs) are rare mesenchymal neoplasms of the gastrointestinal tract characterised by the over expression of the tyrosin kinase receptor c-KIT, representing only 0.1-3% of all gastrointestinal cancers with an estimated incidence of 15 per million people. We report two GISTs treated in our hospital which presented as common surgical abdominal problems along with a review of the literature.