Dim light at night increases body mass of female mice

摘要

During the past century, the prevalence of light at night has increased in parallel with obesity rates. Dim light at night (dLAN) increases body mass in male mice. However, the effects of light at night on female body mass remain unspecified. Thus, female mice were exposed to a standard light/dark (LD; 16 h light at similar to 150 lux/8 h dark at similar to 0 lux) cycle or to light/dim light at night (dLAN; 16 h light at similar to 150 lux/8 h dim light at similar to 5 lux) cycles for six weeks. Females exposed to dLAN increased the rate of change in body mass compared to LD mice despite reduced total food intake during weeks five and six, suggesting that dLAN disrupted circadian rhythms resulting in deranged metabolism.