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Microelectronic sensors for measurement of electromagnetic fields of living cells and experimental results

机译:用于活细胞电磁场测量的微电子传感器和实验结果

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摘要

Microelectronic sensors are used for measurements of electromagnetic fields generated by synchronized cultures of yeast cells. Cold sensitive mutant tub2-401 of Saccharomyces cerevisiae is used. The measured electromagnetic signals in the frequency range from 8 to 9 MHz are compared with evolution of the reassembled microtubules. The detected signals peak in the time interval 25-30 min and 45-60 min after the release of the cells from the restrictive to the permissive temperature. The first maximum corresponds to the stage when the mitotic spindle is formed and binds chromatids. The second maximum is measured when the processes of anaphase A and of anaphase B take place.
机译:微电子传感器用于测量由酵母细胞同步培养产生的电磁场。使用啤酒酵母的冷敏感突变体tub2-401。将在8到9 MHz频率范围内测得的电磁信号与重新组装的微管的演变进行比较。检测到的信号在细胞从限制温度释放到允许温度后的25-30分钟和45-60分钟的时间间隔达到峰值。第一最大值对应于有丝分裂纺锤体形成并结合染色单体的阶段。当发生后期A和后期B的过程时,将测量第二个最大值。

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