在宅中心静脈栄養法（HPN）における総合ビタミン剤配合型高カロリー輸液キット製剤の有用性検討

摘要

在宅中心静脈栄養（HPN）を行うには病院と居宅の違いに留意し，感染リスクの低減化，操作の簡便化および患者のQOLの向上を図る必要がある。操作の簡便化については，総合ビタミン剤の安定性を配慮しっっ，だれがいつ混注作業を行うかの課題が存在する。 今回，シリンジや注射針などを使用せず総合ビタミン剤を配合する高カロリー輸液キット製剤が発売された。そこでわれわれは，医療従事者およびHPN患者 家族を対象とし，混注に要する時間の測定とアンケート調査を行い，本製剤の操作の簡便性および有用性を検討した。 混注に要する時間は，従来法と比較し有意に短縮された。 アンケートにおいては備蓄性，操作の簡便性が特に評価された。本製品により，患者宅での混注作業における無菌性の維持，異物混入の機会減少が図れる。また本製剤は室温保存ができ備蓄性に優れるので，天災への備えや旅行時の携帯性を考慮すると，HPN患者 家族のQOLの向上に役立つと期待できるWhen home parenteral nutrition (HPN) is instituted, one should aim at reducting the risk of infections, simplifying the operation, and improving the patient's QOL, while considering the differences between the hospital and home, As for simplification of the operation, the problem is who and when to prepare the TPN while paying attention to the stability of multivitamins,. Recently, a TPN kit that includes multivitamins and does not need a syringe or an injection needle to add vitamins to the TPN preparation was launched Accordingly, we conducted a study to examine the simplicity of the procedure and usefulness of the product on the basis of time required to add other components to the TPN preparation, as assessed by questionnaire. The subjects of the study were medical care providers as well as patients on HPN and their families. The time required for TPN admixtures was significantly shorter compared with the conventional method According to the questionnaire, the storability and easiness of the procedure were particularly highly appreciated,. This product has the advantage that sterility can be maintained at home, that contamination with foreign bodies can be reduced, and that it can be stored at room temperature. Since it can be preserved in preparation for natural disasters and can be carried around during travel, it is expected to