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Update in management of male urinary incontinence: Injectables, balloons, minimally invasive approaches

机译:男性尿失禁的管理更新:注射剂,球囊,微创方法

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PURPOSE OF REVIEW: The surgical armamentarium for stress urinary incontinence in men ranges from minimally invasive endoscopic procedures to artificial urinary sphincter implantation. In this rapidly moving field, respective indications of surgical options are also evolving, as evidence for the use of innovative devices is growing. This review is focused on recent data about injectables, stem cells and periurethral balloons implantation. RECENT FINDINGS: Periurethral injections are probably the most minimally invasive options, but are considered of low efficacy, with a high recurrence rate in the short term. Reinjections are often needed. However, the market share of periurethral bulking is decreasing relatively slowly. Innovative, so-called regenerative therapies, including injection of biological material, stem cells, myoblasts and muscle strings implantation have shown promising results but did not yet reach maturity for daily use in the clinic. Periurethral balloons implantation shows an acceptable success rate at mid-term follow-up, but are associated with a high rate of complications and reoperations. SUMMARY: Indications of periurethral bulking are decreasing. Regenerative therapies are still under investigation in men, and long-term studies are still required. Comparative studies against male slings and other compression devices are still awaited to accurately determine the role of periurethral balloons implantation.
机译:审查的目的:男性压力性尿失禁的外科武器库的范围从微创内窥镜手术到人工尿道括约肌植入。在这个飞速发展的领域,随着使用创新器械的证据不断增多,有关手术选择的各种指征也在不断发展。这篇综述集中在有关注射剂,干细胞和尿道周围球囊植入的最新数据。最近的发现:尿道周注射可能是最微创的选择,但被认为疗效低,短期内复发率高。经常需要重新注射。但是,尿道周围肿块的市场份额下降相对缓慢。创新的所谓再生疗法,包括生物材料的注射,干细胞,成肌细胞和肌弦植入,已显示出令人鼓舞的结果,但尚未达到临床日常使用的成熟度。尿道周球囊植入术在中期随访中显示出可接受的成功率,但与并发症和再次手术的发生率高相关。摘要:尿道周围肿大的迹象正在减少。男性仍在研究再生疗法,并且仍需要长期研究。仍在等待针对男性吊索和其他压缩装置的比较研究,以准确确定尿道周围球囊植入的作用。

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