Implementation of a generic liquid chromatographic method development workflow: Application to the analysis of phytocannabinoids and Cannabis sativa extracts

Fekete Szabolcs; Sadat-Noorbakhsh Vida; Schelling Cedric; Molnar Imre; Guillarme Davy; Rudaz Serge; Veuthey Jean-Luc

首页> 外文期刊>Journal of Pharmaceutical and Biomedical Analysis: An International Journal on All Drug-Related Topics in Pharmaceutical, Biomedical and Clinical Analysis >Implementation of a generic liquid chromatographic method development workflow: Application to the analysis of phytocannabinoids and Cannabis sativa extracts

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Implementation of a generic liquid chromatographic method development workflow: Application to the analysis of phytocannabinoids and Cannabis sativa extracts

机译：仿制液相色谱法开发工作流程的实施：应用于植物植物和大麻苜蓿提取物的分析

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A generic liquid chromatographic method development workflow was developed and successfully applied to the analysis of phytocannabinoids and Cannabis sativa extracts. Our method development procedure consists in four steps:

机译：开发了通用液体色谱法开发工作流程，成功地应用于植物植物和大麻苜蓿提取物的分析。我们的方法开发程序包括四个步骤：

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来源
《Journal of Pharmaceutical and Biomedical Analysis: An International Journal on All Drug-Related Topics in Pharmaceutical, Biomedical and Clinical Analysis》 |2018年第2018期|共9页
作者
Fekete Szabolcs; Sadat-Noorbakhsh Vida; Schelling Cedric; Molnar Imre; Guillarme Davy; Rudaz Serge; Veuthey Jean-Luc;
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作者单位

Univ Lausanne Univ Geneva Sch Pharmaceut Sci Rue Michel Servet 1 CH-1206 Geneva 4 Switzerland;

Univ Lausanne Univ Geneva Sch Pharmaceut Sci Rue Michel Servet 1 CH-1206 Geneva 4 Switzerland;

Univ Lausanne Univ Geneva Sch Pharmaceut Sci Rue Michel Servet 1 CH-1206 Geneva 4 Switzerland;

Molnar Inst Appl Chromatog Schneegloeckchenstr 47 D-10407 Berlin Germany;

Univ Lausanne Univ Geneva Sch Pharmaceut Sci Rue Michel Servet 1 CH-1206 Geneva 4 Switzerland;

Univ Lausanne Univ Geneva Sch Pharmaceut Sci Rue Michel Servet 1 CH-1206 Geneva 4 Switzerland;

Univ Lausanne Univ Geneva Sch Pharmaceut Sci Rue Michel Servet 1 CH-1206 Geneva 4 Switzerland;

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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
Cannabinoids; Cannabis; Method development; Robustness test; DryLab; UHPLC;

机译：大麻素;大麻;方法开发;鲁棒性测试;DRYLAB;UHPLC;

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专利

1. Implementation of a generic liquid chromatographic method development workflow: Application to the analysis of phytocannabinoids and Cannabis sativa extracts [J] . Fekete Szabolcs, Sadat-Noorbakhsh Vida, Schelling Cedric, Journal of Pharmaceutical and Biomedical Analysis: An International Journal on All Drug-Related Topics in Pharmaceutical, Biomedical and Clinical Analysis . 2018,第期

机译：仿制液相色谱法开发工作流程的实施：应用于植物植物和大麻苜蓿提取物的分析
2. Development and validation of a generic liquid chromatographic method for the simultaneous determination of five commonly used antimalarial drugs: Application to pharmaceutical formulations and human plasma [J] . Mannemala Sai Sandeep, Nagarajan Janaki Sankarachari Krishnan Journal of separation science. . 2015,第9期

机译：同时测定五种常用抗疟药的通用液相色谱方法的开发和验证：应用于药物制剂和人体血浆
3. Analysis of Terpenes in Cannabis sativa L. Using GC/MS: Method Development, Validation, and Application [J] . Ibrahim Elsayed A., Wang Mei, Radwan Mohamed M., Planta medica: Natural products and medicinal plant research . 2019,第5期

机译：Cannabis Sativa L的Terpenes分析。使用GC / MS：方法开发，验证和应用
4. Characteristics of hemp (Cannabis sativa L.) seed oil extracted with supercritical CO_2 [C] . C. Da Porto, D. Decorti, D. Voinovich, European Meeting on Supercritical Fluids . 2010

机译：大麻（Cannabis Sativa L.）种子油的特征用超临界CO_2提取
5. High-performance liquid chromatographic methods for quantitative assessment of degradation products and extractives in pretreated lignocellulose [D] . Chen, Shou-Feng 2007

机译：高效液相色谱方法，用于定量评估预处理木质纤维素中的降解产物和提取物
6. Development of a High-Performance Liquid Chromatographic Method for Determination of Letrozole in Wistar Rat Serum and its Application in Pharmacokinetic Studies [O] . Sasmita Kumari Acharjya, Subrat Kumar Bhattamisra, Bhanoji Rao E. Muddana, 2012

机译：高效液相色谱法测定Wistar大鼠血清中来曲唑的研制及其在药代动力学研究中的应用
7. Development and application of a LC-MS/MS method for the analysis of plasma bioavailabilities of different cannabinoids after the administration of "Cannabis sativa L." extracts and MarinolTM [O] . Grauwiler Sandra Béatrice 2008

机译：LC-ms / ms方法的开发和应用，用于分析“大麻”给药后不同大麻素的血浆生物利用度提取物和marinolTm
8. Femtomolar Ion-Pair High-Performance Liquid Chromatographic Method for Determining Dns-Polyamine Derivatives of Red Blood Cell Extracts Utilizing an Automated Polylamine Analyzer [R] . Brown, N. D., Strickler, M. P., Whaun, J. M. 1982

机译：利用自动化聚胺分析仪测定红细胞提取物Dns-多胺衍生物的飞摩尔离子对高效液相色谱法

Implementation of a generic liquid chromatographic method development workflow: Application to the analysis of phytocannabinoids and Cannabis sativa extracts

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