Volumetric, acoustic and viscometric studies of l-histidine in aqueous solutions of non-steroid anti-inflammatory drug ketorolac tromethamine at different temperatures

摘要

AbstractIn this investigation density, speed of sound and viscosity ofl-histidine (0.015–0.135) molkg?1in aqueous ketorolac tromethamine solutions (0.1–0.7) molkg?1at various temperatures (293.15, 298.15, 303.15, 308.15 and 308.15) K and at atmospheric pressure were studied. These data were further used to calculate apparent molar volume,VΦ, limiting apparent molar volume,V°Φ, limiting apparent molar volume of transfer,V°Φ,tr, apparent molar isentropic compression,KΦ,S, limiting molar isentropic compression,K°Φ,S, limiting apparent molar isentropic compression of transfer,K°Φ,S,tr, hydration number,nH, Jones-Dole coefficient-B,B, viscosity B-coefficients of transfer,Btrand the activation parameters, ?μ°#1and ?μ°#2