Partitioning of thiophene derivatives between solvent and micellar media of cationic surfactant, cetyl trimethyl ammonium bromide

摘要

Abstract This manuscript reports the interaction of thiophene derivatives i.e. 5-(2-(benzyloxy) phenyl) thiophene-2-sulfonamide (BPTS) and 5-bromothiophene-2-sulfonamide (BTS) with micellar media of cationic surfactant, cetyl trimethylammonium bromide (CTAB) using UV/visible spectroscopy. Quantitative measurement of the degree of solubilization and binding has been calculated in term of partition coefficient (K x ) and binding constant (K b ) respectively while the values of free energy of partition (ΔGp), and free energy of binding (ΔGb) give information about spontaneity of both processes. Graphical abstract Display Omitted Highlights ? CTAB causes red shift in spectra of BPTS and BTS. ? BTS has greater degree of binging and partition with CTAB than BPTS. ? Electrostatic and hydrophobic forces favour partitioning. ]]>