Overview of Recent Strategic Advances in Medicinal Chemistry

Wu Gaochan; Zhao Tong; Kang Dongwei; Zhang Jian; Song Yuning; Namasivayam Vigneshwaran; Kongsted Jacob; Pannecouque Christophe; De Clercq Erik; Poongavanam Vasanthanathan; Liu Xinyong; Zhan Peng

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Overview of Recent Strategic Advances in Medicinal Chemistry

机译：近期药用化学战略进展概述

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Introducing novel strategies, concepts, and technologies that speed up drug discovery and the drug development cycle is of great importance both in the highly competitive pharmaceutical industry as well as in academia. This Perspective aims to present a "big-picture" overview of recent strategic innovations in medicinal chemistry and drug discovery.

机译：介绍加速药物发现和药物开发周期的新型策略，概念和技术在高竞争激烈的制药行业以及学术界方面都具有重要意义。这种观点旨在展示“大局”概述药用化学和药物发现中最近的战略性创新。

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《Journal of Medicinal Chemistry 》 |2019年第21期| 共40页
作者
Wu Gaochan; Zhao Tong; Kang Dongwei; Zhang Jian; Song Yuning; Namasivayam Vigneshwaran; Kongsted Jacob; Pannecouque Christophe; De Clercq Erik; Poongavanam Vasanthanathan; Liu Xinyong; Zhan Peng;
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Shandong Univ Sch Pharmaceut Sci Key Lab Chem Biol Dept Med Chem Minist Educ 44 West Culture Rd Jinan 250012 Shandong Peoples R China;

Shandong Univ Sch Pharmaceut Sci Key Lab Chem Biol Dept Med Chem Minist Educ 44 West Culture Rd Jinan 250012 Shandong Peoples R China;

Shandong Univ Sch Pharmaceut Sci Key Lab Chem Biol Dept Med Chem Minist Educ 44 West Culture Rd Jinan 250012 Shandong Peoples R China;

Shandong Univ Sch Pharmaceut Sci Key Lab Chem Biol Dept Med Chem Minist Educ 44 West Culture Rd Jinan 250012 Shandong Peoples R China;

Shandong Univ Qilu Hosp Dept Clin Pharm Jinan 250012 Shandong Peoples R China;

Univ Bonn Pharmaceut Chem 2 Pharmaceut Inst D-53121 Bonn Germany;

Univ Southern Denmark Dept Phys Chem &

Pharm DK-5230 Odense M Denmark;

Katholieke Univ Leuven Lab Virol &

Chemotherapy Rega Inst Med Res Herestr 49 Postbus 1043 09-A097 B-3000 Leuven Belgium;

Katholieke Univ Leuven Lab Virol &

Chemotherapy Rega Inst Med Res Herestr 49 Postbus 1043 09-A097 B-3000 Leuven Belgium;

Univ Southern Denmark Dept Phys Chem &

Pharm DK-5230 Odense M Denmark;

Shandong Univ Sch Pharmaceut Sci Key Lab Chem Biol Dept Med Chem Minist Educ 44 West Culture Rd Jinan 250012 Shandong Peoples R China;

Shandong Univ Sch Pharmaceut Sci Key Lab Chem Biol Dept Med Chem Minist Educ 44 West Culture Rd Jinan 250012 Shandong Peoples R China;

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正文语种 eng
中图分类药学 ;
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专利

1. Overview of Recent Strategic Advances in Medicinal Chemistry [J] . Wu Gaochan, Zhao Tong, Kang Dongwei, Journal of Medicinal Chemistry . 2019 ,第21期

机译：近期药用化学战略进展概述
2. Tuberculosis: An Overview of the Immunogenic Response, Disease Progression, and Medicinal Chemistry Efforts in the Last Decade toward the Development of Potential Drugs for Extensively Drug-Resistant Tuberculosis Strains [J] . Sharma Akanksha, De Rosa Maria, Singla Neha, Journal of Medicinal Chemistry . 2021 ,第8期

机译：结核病：过去十年来概述了免疫原性反应，疾病进展和药用化学努力，旨在为广泛的耐药结核菌素菌株的潜在药物发展
3. overview on Medicinal Chemistry for Drug Discovery [J] . Radhey Srivastava Medicinal Chemistry . 2021 ,第2期

机译：药物发现药物化学概况
4. Recent advances for handling imbalancement and uncertainty in labelling in medicinal chemistry data analysis [C] . João Carlos Silva de Souza, Suzana Gomes Claudino, Rodolfo da Silva Simões, 2016 SAI Computing Conference . 2016

机译：在药物化学数据分析中处理标签不平衡和不确定性的最新进展
5. Application of Synthetic Organic and Medicinal Chemistry Toward Medical Advances in Cancer, Antibiotics, and Drug Delivery [D] . Lutz, Marlon Ray, Jr. 2018

机译：有机和药物合成化学在癌症，抗生素和药物输送中的医学应用进展
6. Strategic Incorporation of Fluorine into Taxoid Anticancer Agents for Medicinal Chemistry and Chemical Biology Studies [O] . Iwao Ojima -1

机译：战略性地将氟纳入紫杉类抗癌药中用于药物化学和化学生物学研究
7. The Brazilian Medicinal Chemistry from 1998 to 2008 in the Journal of Medicinal Chemistry, Bioorganic and Medicinal Chemistry, Bioorganic and Medicinal Chemistry Letters and European Journal of Medicinal Chemistry [O] . Renato S. Bastos, Bárbara V. da Silva, Angelo C. Pinto 2009

机译：1998年至2008年的《巴西药物化学》，《药物化学，生物有机药物化学》，《生物有机药物化学快报》和《欧洲药物化学杂志》

Overview of Recent Strategic Advances in Medicinal Chemistry

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