Cerebral asymmetry and the lateralization of language: core deficits in schizophrenia as pointers to the gene

摘要

The dimension of asymmetry stands out as the variable that can make sense of observations across fields of investigation, and provides a key to the genetic basis of psychosis. Discordant monozygotic twin studies indicate strongly that the relevant variation is epigenetic; this is consistent with the possibility that the variation is related to recent structural changes (the Xq21.3/ Yp duplicative transposition) on the sex chromosomes.