Effect of Hydrocortisone on Development of Shock Among Patients With Severe Sepsis The HYPRESS Randomized Clinical Trial

Keh Didier; Trips Evelyn; Marx Gernot; Wirtz Stefan P.; Abduljawwad Emad; Bercker Sven; Bogatsch Holger; Briegel Josef; Engel Christoph; Gerlach Herwig; Goldmann Anton; Kuhn Sven-Olaf; Huter Lars; Meier-Hellmann Andreas; Nierhaus Axel; Kluge Stefan; Lehmke Josefa; Loeffler Markus; Oppert Michael; Resener Kerstin; Schadler Dirk; Schuerholz Tobias; Simon Philipp; Weiler Norbert; Weyland Andreas; Reinhart Konrad; Brunkhorst Frank M.

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Effect of Hydrocortisone on Development of Shock Among Patients With Severe Sepsis The HYPRESS Randomized Clinical Trial

机译：氢化松子对严重败血症患者休克休克开发的影响随机临床试验

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IMPORTANCE Adjunctive hydrocortisone therapy is suggested by the Surviving Sepsis Campaign in refractory septic shock only. The efficacy of hydrocortisone in patients with severe sepsis without shock remains controversial.

机译：Survive Sepsis运动中仅仅是难治性化脓性休克的幸存败腐氢鞘酮疗法。氢化可没有休克的严重败血症患者患者的疗效仍然存在争议。

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《JAMA: the Journal of the American Medical Association》 |2016年第17期|共11页
作者
Keh Didier; Trips Evelyn; Marx Gernot; Wirtz Stefan P.; Abduljawwad Emad; Bercker Sven; Bogatsch Holger; Briegel Josef; Engel Christoph; Gerlach Herwig; Goldmann Anton; Kuhn Sven-Olaf; Huter Lars; Meier-Hellmann Andreas; Nierhaus Axel; Kluge Stefan; Lehmke Josefa; Loeffler Markus; Oppert Michael; Resener Kerstin; Schadler Dirk; Schuerholz Tobias; Simon Philipp; Weiler Norbert; Weyland Andreas; Reinhart Konrad; Brunkhorst Frank M.;
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作者单位

Charite Dept Anesthesiol &

Intens Care Med Berlin Germany;

Clin Trial Ctr Leipzig Leipzig Germany;

Univ Hosp RWTH Aachen Dept Intens Care &

Intermediate Care Aachen Germany;

HELIOS Hosp Bad Saarow Dept Intens Care Med Bad Saarow Pieskow Germany;

HELIOS Hosp Bad Saarow Dept Intens Care Med Bad Saarow Pieskow Germany;

Univ Leipzig Dept Anesthesiol &

Intens Care Med Leipzig Germany;

Clin Trial Ctr Leipzig Leipzig Germany;

Klinikum Ludwig Maximilians Univ Dept Anesthesiol Munich Germany;

Inst Med Informat Stat &

Epidemiol Leipzig Germany;

Vivantes Klinikum Neukolln Dept Anesthesia Intens Care Med &

Pain Management Berlin Germany;

Charite Dept Anesthesiol &

Intens Care Med Berlin Germany;

Ernst Moritz Arndt Univ Greifswald Dept Anesthesiol &

Intens Care Med Greifswald Germany;

Zentralklin Bad Berka Dept Anesthesia &

Intens Care Bad Berka Germany;

HELIOS Hosp Erfurt Intens Care Med &

Pain Management Erfurt Germany;

Univ Med Ctr Hamburg Eppendorf Dept Intens Care Med Hamburg Germany;

Univ Med Ctr Hamburg Eppendorf Dept Intens Care Med Hamburg Germany;

Vivantes Humboldt Klinikum Dept Cardiol &

Intens Care Med Berlin Germany;

Inst Med Informat Stat &

Epidemiol Leipzig Germany;

Klinikum Ernst von Bergmann Dept Emergency &

Intens Care Med Potsdam Germany;

HELIOS Hosp Berlin Buch Dept Intens Care Med Berlin Germany;

Univ Med Ctr Schleswig Holstein Dept Anesthesiol &

Intens Care Med Campus Kiel Kiel Germany;

Univ Hosp RWTH Aachen Dept Intens Care &

Intermediate Care Aachen Germany;

Univ Leipzig Dept Anesthesiol &

Intens Care Med Leipzig Germany;

Univ Med Ctr Schleswig Holstein Dept Anesthesiol &

Intens Care Med Campus Kiel Kiel Germany;

Carl von Ossietzky Univ Oldenburg Klinikum Oldenburg Med Campus Dept Anesthesiol Intens Care Med;

Jena Univ Hosp Dept Anesthesiol &

Intens Care Med Jena Germany;

Jena Univ Hosp Ctr Sepsis Control &

Care Ctr Clin Studies Jena Germany;

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原文格式 PDF
正文语种 eng
中图分类医药、卫生;
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入库时间 2022-08-19 19:21:33

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专利

1. Effect of Hydrocortisone on Development of Shock Among Patients With Severe Sepsis The HYPRESS Randomized Clinical Trial [J] . Keh Didier, Trips Evelyn, Marx Gernot, JAMA: the Journal of the American Medical Association . 2016,第17期

机译：氢化松子对严重败血症患者休克休克开发的影响随机临床试验
2. Comparing the effect of hydroxyethyl starch 130/0.4 with balanced crystalloid solution on mortality and kidney failure in patients with severe sepsis (6S - Scandinavian Starch for Severe Sepsis/Septic Shock trial): Study protocol, design and rationale for a double-blinded, randomised clinical trial [J] . Anders Perner, Nicolai Haase, J?rn Wetterslev, Trials . 2011,第1期

机译：比较羟乙基淀粉130 / 0.4与平衡的晶体溶液对严重脓毒症患者的死亡率和肾衰竭的影响（6S-严重脓毒症/脓毒性休克试验的斯堪的纳维亚淀粉）：双盲，随机研究的研究方案，设计和原理临床试验
3. Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock The VITAMINS Randomized Clinical Trial [J] . Edney Samantha J., Hunt Anna L., Judd Harriet L., JAMA: the Journal of the American Medical Association . 2020,第5期

机译：维生素C，氢化松环和硫胺素对氢化可的来的影响及时在脓毒素休克患者中存在和无血管加压蛋白支持维生素随机临床试验
4. Relation of heart rate variability to serum levels of C-reactive protein in patients with severe sepsis and septic shock [C] . Papaioannou V.P., Dragoumanis C.D., Pneumatikos I.P. Computers in Cardiology, 2009 . 2009

机译：严重败血症和败血性休克患者心率变异性与血清C反应蛋白水平的关系
5. Trials and tribulations: Using patients' and physicians' preferences to enhance the efficiency and ethics of randomized clinical trials [D] . Halpern, Scott David 2002

机译：试验和磨难：利用患者和医生的偏好来提高随机临床试验的效率和伦理
6. Comparing the effect of hydroxyethyl starch 130/0.4 with balanced crystalloid solution on mortality and kidney failure in patients with severe sepsis (6S - Scandinavian Starch for Severe Sepsis/Septic Shock trial): Study protocol design and rationale for a double-blinded randomised clinical trial [O] . Anders Perner, Nicolai Haase, Jørn Wetterslev, 2011

机译：比较羟乙基淀粉130 / 0.4和平衡的晶体溶液对严重脓毒症患者的死亡率和肾衰竭的影响（6S-斯堪的纳维亚淀粉用于严重脓毒症/败血性休克试验）：双盲随机研究的研究方案设计和原理临床试验
7. Effect of Hydrocortisone on Development of Shock Among Patients With Severe Sepsis : The HYPRESS Randomized Clinical Trial [O] . Keh, Didier, Trips, Evelyn, Goldmann, Anton, 2016

机译：氢化可的松对严重脓毒症患者休克发展的影响：HYPRESS随机临床试验

Effect of Hydrocortisone on Development of Shock Among Patients With Severe Sepsis The HYPRESS Randomized Clinical Trial

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