TCF7L2 Genetic Variation Augments Incretin Resistance and Influences Response to a Sulfonylurea and Metformin: The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH)

Srinivasan Shylaja; Kaur Varinderpal; Chamarthi Bindu; Littleton Katherine R.; Chen Ling; Manning Alisa K.; Merino Jordi; Thomas Melissa K.; Hudson Margo; Goldfine Allison; Florez Jose C.

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TCF7L2 Genetic Variation Augments Incretin Resistance and Influences Response to a Sulfonylurea and Metformin: The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH)

机译：TCF7L2遗传变异增强抗性抗性和影响对磺酰脲类和二甲双胍的反应：本研究了解人体（糖-MGH）对二甲双胍和粘吡格肽的急性反应遗传学的研究

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《Diabetes care》 |2018年第3期|共8页
作者
Srinivasan Shylaja; Kaur Varinderpal; Chamarthi Bindu; Littleton Katherine R.; Chen Ling; Manning Alisa K.; Merino Jordi; Thomas Melissa K.; Hudson Margo; Goldfine Allison; Florez Jose C.;
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作者单位

Massachusetts Gen Hosp Pediatr Endocrine Unit Boston MA 02114 USA;

Massachusetts Gen Hosp Diabet Unit Boston MA 02114 USA;

Brigham &

Womens Hosp Div Endocrinol Diabet &

Hyperten Boston MA 02115 USA;

Massachusetts Gen Hosp Diabet Unit Boston MA 02114 USA;

Massachusetts Gen Hosp Diabet Unit Boston MA 02114 USA;

Massachusetts Gen Hosp Diabet Unit Boston MA 02114 USA;

Massachusetts Gen Hosp Diabet Unit Boston MA 02114 USA;

Eli Lilly &

Co Indianapolis IN USA;

Brigham &

Womens Hosp Div Endocrinol Diabet &

Hyperten Boston MA 02115 USA;

Harvard Med Sch Dept Med Boston MA 02115 USA;

Massachusetts Gen Hosp Diabet Unit Boston MA 02114 USA;

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原文格式 PDF
正文语种 eng
中图分类内分泌腺疾病及代谢病;
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1. TCF7L2 Genetic Variation Augments Incretin Resistance and Influences Response to a Sulfonylurea and Metformin: The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH) [J] . Srinivasan Shylaja, Kaur Varinderpal, Chamarthi Bindu, Diabetes care . 2018,第3期

机译：TCF7L2遗传变异增强抗性抗性和影响对磺酰脲类和二甲双胍的反应：本研究了解人体（糖-MGH）对二甲双胍和粘吡格肽的急性反应遗传学的研究
2. Genetic variations in TCF7L2 influence therapeutic response to sulfonylureas in Indian diabetics [J] . Dhawan Dipali, Padh Harish Diabetes research and clinical practice . 2016,第Null期

机译：TCF7L2的遗传变异影响印度糖尿病患者对磺酰脲类药物的治疗反应
3. Impact of KCNJ11, TCF7L2, SLC30A8, IGF2BP2, PPARG, SLC47A1, STK11, HHEX, KCNQ1, CDKAL1, FTO, CYP2C9, ADIPOQ, CAPN10 gene polymorphisms on risk of type 2 diabetes and therapeutic response to sulfonylurea and metformin therapy [J] . Nagaraja Phani, Padmalatha Rai, Prabha Adhikari, Molecular cytogenetics . 2014,第S1期

机译：KCNJ11，TCF7L2，SLC30A8，IGF2BP2，PPARG，SLC47A1，STK11，HHEX，KCNQ1，CDKAL1，FTO，CYP2C9，ADIPOQ，CAPN10基因多态性对2型糖尿病风险以及对磺酰脲和二甲双胍治疗的治疗反应的影响
4. Immunology and Genetics: Phenotypic, Genetic and Epigenetic Variation of Bovine Immune Responses and Disease Resistance [C] . Bonnie A. Mallard Annual Conference of American Association of Bovine Practitioners . 2007

机译：免疫学和遗传学：表型，遗传和表观遗传变异牛免疫应答和抗病性
5. Use of molecular genetics and functional genomics to: (i) Understand dichlorodiphenyltrichloroethane (DDT) resistance in Drosophila melanogaster and (ii) identify vulnerable target gene systems in Pediculus humanus humanus (body louse) and Callosobrucus maculatus (Cowepea weevil). [D] . Pedra, Joao Helbert Ferreira. 2004

机译：利用分子遗传学和功能基因组学来：（i）了解黑腹果蝇（Drosophila melanogaster）对二氯二苯基三氯乙烷（DDT）的抗性，以及（ii）在人类Pediculus humanus humanus（体虱）和Callosobrucus maculatus（Cowepea weevil）中识别易受攻击的靶基因系统。
6. TCF7L2 Genetic Variation Augments Incretin Resistance and Influences Response to a Sulfonylurea and Metformin: The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH) [O] . Shylaja Srinivasan, Varinderpal Kaur, Bindu Chamarthi, 2018

机译：TCF7L2遗传变异增强肠抑素抗性并影响对磺酰脲和二甲双胍的反应：了解人类对二甲双胍和格列吡嗪急性反应的遗传学研究（SUGAR-MGH）
7. TCF7L2Genetic Variation Augments Incretin Resistance and Influences Response to a Sulfonylurea and Metformin: The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH) [O] . Shylaja Srinivasan, Varinderpal Kaur, Bindu Chamarthi, 2018

机译：TCF7L2Genetic变异增强增生素抗性和对磺酰脲和二甲双胍的反应影响：本研究了解人体（糖-MGH）对二甲双胍和粘合剂的急性反应的遗传

TCF7L2 Genetic Variation Augments Incretin Resistance and Influences Response to a Sulfonylurea and Metformin: The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH)

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