Effect of HIV-exposure and timing of antiretroviral treatment initiation in children living with HIV on antibody persistence and memory responses to Haemophilus influenzae type b and pneumococcal polysaccharide-protein conjugate vaccines

Madhi Shabir A.; Izu Alane; Violari Avy; Cotton Mark F.; Jean-Philippe Patrick; Otwombe Kennedy; Adrian Peter V

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Effect of HIV-exposure and timing of antiretroviral treatment initiation in children living with HIV on antibody persistence and memory responses to Haemophilus influenzae type b and pneumococcal polysaccharide-protein conjugate vaccines

机译：艾滋病毒治疗抗逆转录病毒治疗发生与艾滋病毒抗体持续和记忆反应对嗜血杆菌血液血栓血液磷酸型血糖多糖 - 蛋白缀合物疫苗疫苗疫苗疫苗疫苗的影响

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Background: We investigated the effect of in utero HIV-exposure, timing of antiretroviral treatment (ART) initiation, and ART interruption on memory responses and persistence of immunity induced by pneumococcal (PCV) and Haemophilus influenzae type b (HibCV) polysaccharide-protein conjugate vaccines.

机译：背景：我们调查了抗逆转录病毒治疗（ART）启动，术记忆响应的时序和肺炎球菌（PCV）和嗜血杆菌型多糖 - 蛋白蛋白缀合物诱导的记忆响应和持续性的抗逆转录病毒治疗（ART）开始和持续性的效果。疫苗。

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来源
《Vaccine》 |2020年第12期|共9页
作者
Madhi Shabir A.; Izu Alane; Violari Avy; Cotton Mark F.; Jean-Philippe Patrick; Otwombe Kennedy; Adrian Peter V;
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作者单位

Univ Witwatersrand Fac Hlth Sci MRC Resp &

Meningeal Pathogens Res Unit Johannesburg South Africa;

Univ Witwatersrand Fac Hlth Sci MRC Resp &

Meningeal Pathogens Res Unit Johannesburg South Africa;

Univ Witwatersrand Fac Hlth Sci Perinatal HIV Res Unit Johannesburg South Africa;

Stellenbosch Univ Fac Med Ubuntu Family Ctr Dept Paediat &

ChildMed &

Hlth Sci Clin Res Unit Cape Town South Africa;

NIAID Div AIDS Bethesda MD 20892 USA;

Univ Witwatersrand Fac Hlth Sci Perinatal HIV Res Unit Johannesburg South Africa;

Univ Witwatersrand Fac Hlth Sci MRC Resp &

Meningeal Pathogens Res Unit Johannesburg South Africa;

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原文格式 PDF
正文语种 eng
中图分类医学免疫学;
关键词
Streptococcus pneumoniae; Pneumococcal conjugate vaccine; Haemophilus influenzae type b conjugate; vaccine; HIV exposure; HIV; Opsonophagocytic assay; Memory responses; Antibody persistence;

机译：肺炎链球菌;肺炎球菌缀合物疫苗;嗜血杆菌流感型B型缀合物;疫苗;艾滋病毒暴露;艾滋病毒;艾滋病毒;Opsonophagocytic测定;记忆反应;抗体持久性;

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1. Effect of HIV-exposure and timing of antiretroviral treatment initiation in children living with HIV on antibody persistence and memory responses to Haemophilus influenzae type b and pneumococcal polysaccharide-protein conjugate vaccines [J] . Madhi Shabir A., Izu Alane, Violari Avy, Vaccine . 2020,第12期

机译：艾滋病毒治疗抗逆转录病毒治疗发生与艾滋病毒抗体持续和记忆反应对嗜血杆菌血液血栓血液磷酸型血糖多糖 - 蛋白缀合物疫苗疫苗疫苗疫苗疫苗的影响
2. Immunogenicity of Haemophilus influenzae Type b Polysaccharide-Protein Conjugate Vaccines in Children With Conditions Associated With Impaired Antibody Responses to Type b Polysaccharide Vaccine [J] . Dan M. Granoff, Geoffrey A. Weinberg Pediatrics: Official Publication of the American Academy of Pediatrics . 1990,第4期

机译：乙型流感嗜血杆菌多糖-蛋白质结合疫苗的免疫原性与对b型多糖疫苗的抗体应答受损的儿童相关
3. Persistence of Antibody and Booster Responses to Reimmunization With Haemophilus influenzae Type b Polysaccharide and Polysaccharide Diphtheria Toxoid Conjugate Vaccines in Children Initially Immunized at 15 to 24 Months of Age [J] . . Chung-E-Chiu, Carol D. Berkowitz, Colin D. Marchant, Pediatrics: Official Publication of the American Academy of Pediatrics . 1990,第3期

机译：最初在15至24个月龄免疫的儿童中，b型流感嗜血杆菌多糖和多糖白喉类毒素结合疫苗对抗体和加强免疫应答的持久性
4. Haemophilus influenzae Type b Conjugate Vaccine with a Synthetic Capsular Polysaccharide Antigen: Chemical View [C] . Vicente Verez Bencomo, Rene Roy, Maria C. Rodriguez, American Chemical Society . 2008

机译：Hemophilus流感B型缀合物疫苗，具有合成囊多糖抗原：化学视图
5. Optimization of pediatric antiretroviral therapy in sub-Saharan Africa: Timing of initiation in HIV/TB co-infected children and using gains in weight, height, or CD4 count to monitor the response. [D] . Yotebieng, Marcel. 2009

机译：撒哈拉以南非洲地区小儿抗逆转录病毒疗法的优化：HIV / TB合并感染儿童的开始接种时间，并利用体重，身高或CD4计数的增加来监测反应。
6. Antibody Persistence in Young Children 5 Years after Vaccination with a Combined Haemophilus influenzae Type b-Neisseria meningitidis Serogroup C Conjugate Vaccine Coadministered with Diphtheria-Tetanus-Acellular Pertussis-Based and Pneumococcal Conjugate Vaccines [O] . Juan Carlos Tejedor, Jerzy Brzostek, Ryszard Konior, 2016

机译：联合使用流感嗜血杆菌b型脑膜炎奈瑟氏球菌血清群C结合疫苗联合白喉-破伤风-无细胞百日咳和肺炎球菌结合疫苗的5岁儿童的抗体持久性
7. Variable region expression in the antibody responses of infants vaccinated with Haemophilus influenzae type b polysaccharide-protein conjugates. Description of a new lambda light chain-associated idiotype and the relation between idiotype expression, avidity, and vaccine formulation. The Collaborative Vaccine Study Group. [O] . Granoff, D M, Shackelford, P G, Holmes, S J, 1993

机译：接种乙型流感嗜血杆菌多糖-蛋白结合物的婴儿的抗体反应中的可变区表达。新的λ轻链相关的独特型的描述以及独特型表达，亲和力和疫苗制剂之间的关系。疫苗合作研究小组。

Effect of HIV-exposure and timing of antiretroviral treatment initiation in children living with HIV on antibody persistence and memory responses to Haemophilus influenzae type b and pneumococcal polysaccharide-protein conjugate vaccines

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