Megadose Bone Marrow and Regulatory T cells for the Induction of Immune Tolerance in Non-Human Primates Through Durable Mixed Hematopoietic Chimerism Across MHC-barriers

Alonso-Guallart Paula; Duran-Struuck Raimon; Stern Jeffrey; Berglund Erik; Llore Nathaly; Zitsman Jonah; Pierre Genevieve; Kofman Sigal; Danton Makenzie; Gokova Samanta; Lopes Emily; McMurchy Alicia; Tang Qizhi; Levings Megan; Sykes Megan; Griesemer Adam

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Megadose Bone Marrow and Regulatory T cells for the Induction of Immune Tolerance in Non-Human Primates Through Durable Mixed Hematopoietic Chimerism Across MHC-barriers

机译：通过MHC屏障耐用的混合造血逆变，蛋白酶骨髓和调节性T细胞诱导非人类原始化物中的免疫耐受性

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来源
《Transplantation: Official Journal of the Transplantation Society》 |2018年第9suppla期|共2页
作者
Alonso-Guallart Paula; Duran-Struuck Raimon; Stern Jeffrey; Berglund Erik; Llore Nathaly; Zitsman Jonah; Pierre Genevieve; Kofman Sigal; Danton Makenzie; Gokova Samanta; Lopes Emily; McMurchy Alicia; Tang Qizhi; Levings Megan; Sykes Megan; Griesemer Adam;
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作者单位

Columbia Univ Columbia Ctr Transnat Immunol New York NY USA;

Columbia Univ Columbia Ctr Transnat Immunol New York NY USA;

Columbia Univ Columbia Ctr Transnat Immunol New York NY USA;

Columbia Univ Columbia Ctr Transnat Immunol New York NY USA;

Columbia Univ Columbia Ctr Transnat Immunol New York NY USA;

Columbia Univ Columbia Ctr Transnat Immunol New York NY USA;

Columbia Univ Columbia Ctr Transnat Immunol New York NY USA;

Columbia Univ Columbia Ctr Transnat Immunol New York NY USA;

Columbia Univ Columbia Ctr Transnat Immunol New York NY USA;

Columbia Univ Columbia Ctr Transnat Immunol New York NY USA;

Columbia Univ Columbia Ctr Transnat Immunol New York NY USA;

Univ British Columbia Dept Surg Vancouver BC Canada;

Univ Calif San Francisco Dept Surg San Francisco CA 94143 USA;

Columbia Univ Columbia Ctr Transnat Immunol New York NY USA;

Columbia Univ Columbia Ctr Transnat Immunol New York NY USA;

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正文语种 eng
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1. Megadose Bone Marrow and Regulatory T cells for the Induction of Immune Tolerance in Non-Human Primates Through Durable Mixed Hematopoietic Chimerism Across MHC-barriers [J] . Alonso-Guallart Paula, Duran-Struuck Raimon, Stern Jeffrey, Transplantation: Official Journal of the Transplantation Society . 2018,第9Suppla期

机译：通过MHC屏障耐用的混合造血逆变，蛋白酶骨髓和调节性T细胞诱导非人类原始化物中的免疫耐受性
2. Induction of Durable Mixed Hematopoietic Chimerism and Immune Tolerance in Monkeys [J] . Guallart Paula Alonso, Zitsman Jonah, Sondermeijer Hugo, Biology of blood and marrow transplantation: journal of the American Society for Blood and Marrow Transplantation . 2015,第2Suppla1期

机译：在猴子中诱导持久的混合造血嵌合体和免疫耐受
3. Induction of mixed chimerism using combinatory cell-based immune modulation with mesenchymal stem cells and regulatory T cells for solid-organ transplant tolerance [J] . ImK.-I., ParkM.-J., KimN., Stem cells and development . 2014,第19期

机译：基于结合细胞的免疫调节与间充质干细胞和调节性T细胞诱导的混合嵌合体对实体器官移植的耐受性
4. Vascularized bone marrow transplantation leads to higher levels of hematopoietic chimerism than conventional cellular bone marrow transplantation [C] . Zamfirescu D, Popovicu C, Bularda A, World Society for Reconstructive Microsurgery . 2011

机译：血管化的骨髓移植导致比常规细胞骨髓移植更高水平的造血逆变
5. The impact of obesity on bone marrow hematopoietic stem cell function and acute immune response. [D] . Krishnamoorthy, Divya. 2017

机译：肥胖对骨髓造血干细胞功能和急性免疫反应的影响。
6. Abstract 47: Delayed Tolerance Induction Protocol for Vascularized Composite Allografts in Non-Human Primates: The Immunomodulatory Effect of Donor Bone Marrow Transplantation Does Not Prevent the Development of Chronic Rejection in the Absence of Durable Mixed Chimerism [O] . Alexandre G. Lellouch, Zhi Yang Ng, Ivy A. Rosales, 2017

机译：摘要47：非人类灵长类中血管化复合同种异体移植的延迟耐受诱导方案：在没有持久性混合嵌合体的情况下供体骨髓移植的免疫调节作用不能阻止慢性排斥反应的发展。
7. Induction of Durable Mixed Hematopoietic Chimerism and Immune Tolerance in Monkeys [O] . Guallart Paula Alonso, Zitsman Jonah, Sondermeijer Hugo, 2015

机译：在猴子中诱导持久的混合造血嵌合体和免疫耐受

Megadose Bone Marrow and Regulatory T cells for the Induction of Immune Tolerance in Non-Human Primates Through Durable Mixed Hematopoietic Chimerism Across MHC-barriers

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