Alogliptin, a potent and selective dipeptidyl peptidase-IV inhibitor for the treatment of type 2 diabetes.

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Alogliptin, a potent and selective dipeptidyl peptidase-IV inhibitor for the treatment of type 2 diabetes.

机译：阿格列汀，一种有效的选择性二肽基肽酶-IV抑制剂，用于治疗2型糖尿病。

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Takeda San Diego Inc is developing alogliptin, a small-molecule, orally available dipeptidyl peptidase IV (DPP IV) inhibitor, for the potential treatment of type 2 diabetes. In January 2008, Takeda announced that an NDA for alogliptin had been submitted to the FDA.

机译：武田圣地亚哥公司正在开发阿格列汀，这是一种小分子，可口服的二肽基肽酶IV（DPP IV）抑制剂，可用于治疗2型糖尿病。武田公司在2008年1月宣布，阿格列汀的NDA已提交给FDA。

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《Current opinion in investigational drugs》 |2008年第4期|共12页
作者
Deacon CF;
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正文语种 eng
中图分类药学;
关键词
Roman Numeral IV; therapeutic aspects; Peptide Hydrolases; Diabetes Mellitus; Non-Insulin-Dependent; 肽水解酶类; 糖尿病; 非胰岛素依赖型;

机译：Roman Numeral IV;therapeutic aspects;Peptide Hydrolases;Diabetes Mellitus;Non-Insulin-Dependent;肽水解酶类;糖尿病;非胰岛素依赖型;

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1. Alogliptin, a potent and selective dipeptidyl peptidase-IV inhibitor for the treatment of type 2 diabetes. [J] . Deacon CF Current opinion in investigational drugs . 2008,第4期

机译：阿格列汀，一种有效的选择性二肽基肽酶-IV抑制剂，用于治疗2型糖尿病。
2. RBx-0597, a potent, selective and slow-binding inhibitor of dipeptidyl peptidase-IV for the treatment of type 2 diabetes. [J] . Singh S, Roy S, Sethi S, European Journal of Pharmacology: An International Journal . 2011,第1a3期

机译：RBx-0597，一种二肽基肽酶-IV的有效，选择性和缓慢结合抑制剂，可用于治疗2型糖尿病。
3. Alogliptin: a new, highly selective dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes. [J] . Pratley RE Expert opinion on pharmacotherapy . 2009,第3期

机译：阿格列汀：一种新型的，高度选择性的二肽基肽酶-4抑制剂，用于治疗2型糖尿病。
4. Potent and selective 2-oxoamide inhibitors of phospholipases A2 as novel medicinal agents for the treatment of inflammatory diseases [C] . Efrosini Barbayianni, Georgia Antonopoulou, George Kokotos IUPAC World Congress on Chemistry . 2015

机译：磷脂酶A2的有效和选择性的2-氧代咪唑抑制剂作为治疗炎性疾病的新型药剂
5. Screening, Extraction, Isolation and Characterization of a Dipeptidyl Peptidase-IV (DPP-IV) Inhibitor From Ayurvedic and Chinese Herbs [D] . Dai, Fangteng 2018

机译：阿育吠陀和中草药中二肽基肽酶-IV（DPP-IV）抑制剂的筛选，提取，分离和表征
6. Erratum. Alogliptin a Dipeptidyl Peptidase 4 Inhibitor Prevents the Progression of Carotid Atherosclerosis in Patients With Type 2 Diabetes: The Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A). Diabetes Care 2016;39:139–148 [O] . Tomoya Mita, Naoto Katakami, Hidenori Yoshii, 2017

机译：勘误表。阿格列汀一种二肽基肽酶4抑制剂可预防2型糖尿病患者的颈动脉粥样硬化进展：阿格列汀对糖尿病性动脉硬化（SPEAD-A）的预防作用研究。糖尿病护理2016; 39：139–148
7. Discovery of 2-4-{{2-(2S, 5R)-2-Cyano-5-ethynyl-1-pyrrolidinyl-2-oxoethylamino-4-methyl-1-piperidinyl-4-pyridinecarboxylic Acid (ABT-279): A Very Potent, Selective, Effective, and Well-Tolerated Inhibitor of Dipeptidyl Peptidase-IV, Useful for the Treatment of Diabetes [O] . -1

机译：发现2- 4 - {2 - （2S，5R）-2-氰基-5-乙炔基-1-吡咯烷基 -2-氧乙基氨基 -4-甲基-1-哌啶基 -4-吡啶羧酸（ABT-279）：二肽肽肽酶-IV的非常有效，选择性，有效和耐受良好的抑制剂，可用于治疗糖尿病

Alogliptin, a potent and selective dipeptidyl peptidase-IV inhibitor for the treatment of type 2 diabetes.

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