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Silver-ceria stabilized zirconia composite coatings on titanium for potential implant applications

机译:钛合金稳定氧化锆复合涂料钛潜在植入物应用

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摘要

Surface tailoring of titanium (Ti) implant is an effective way to prevent the initial bacterial adhesion and to improve the biocompatibility of the implants. In view of that, single layered silver (Ag)-ceria stabilized zirconia (CeSZ) nanocomposite coatings were developed on titanium substrates by co-evaporation method using electron beam physical vapor deposition (EBPVD) technique. The concentration of silver was varied from 0, 5 and 10 weight percentage and their microstructure, morphology, bacterial adhesion and corrosion properties were analyzed. Silver-ceria stabilized zirconia nanocomposite coatings have shown superior corrosion resistance than uncoated Ti substrate. Antibacterial efficiency of the coated and uncoated Ti substrates were evaluated using E. coli bacterial strain. Cytotoxic behavior of silver doped and undoped CeSZ coating was carried out in 3T3 mouse fibroblast cells. Electrochemical impedance spectroscopy (EIS) analysis indicated that higher corrosion resistance was observed in 5 wt% Ag added CeSZ nanocomposite coating system than other coated and uncoated substrates.
机译:钛(Ti)植入物的表面剪裁是防止初始细菌粘合性并改善植入物的生物相容性的有效方法。鉴于此,通过使用电子束物理气相沉积(EBPVD)技术,通过共蒸发方法在钛基材上开发单层银(Ag)稳定的氧化锆(CESZ)纳米复合涂层。将银的浓度从0,5和10重量百分比变化,分析了微观结构,形态,细菌粘附和腐蚀性。银稳定的氧化锆纳米复合涂层显示出比未涂覆的Ti底物优异的耐腐蚀性。使用大肠杆菌细菌菌株评价涂覆和未涂覆的Ti底物的抗菌效率。在3T3小鼠成纤维细胞中进行银掺杂和未掺杂的CESZ涂层的细胞毒性行为。电化学阻抗光谱(EIS)分析表明,在5wt%Ag中,在另外的涂覆和未涂覆的基材中,在5wt%Ag中观察到更高的耐腐蚀性。

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