Acute Respiratory Distress Syndrome-Past, Present and Future

摘要

For the past three to four decades, the onset of acute respiratory distress syndrome (ARDS) has brought substantial insight into its epidemiology and pathophysiology. It is characterised by an acute lung injury resulting in widespread pulmonary oedema due to increased alveolar capillary permeability. Acute lung injury arises from the damaging effects of inflammatory mediators. Treatment of ARDS involves various modalities of supportive care categorised as ventilator and non-ventilator measures. Berlin's conference consensus definition of ARDS has been widely accepted in defining and categorising ARDS. The promising therapies for future include use of statins, aspirin,