CANNABINOIDS COULD HELP MANAGE SPASTICITY

摘要

An oral spray containing cannabinoids is effective at reducing spasticity symptoms in motor neurone disease(MND),study results published in The Lancet Neurology(13 December 2018)have shown.The randomised,double-blind,phase II trial involved 60 patients who were randomly assigned to placebo or an oromuoosal spray containing delta-9-tetrahydrocannabinol and cannabidiol.Patients self-escalated their dose during the first two weeks and then maintained that dose for the remaining four weeks of the trial.