Long-chain polyunsaturated fatty acids, gestation duration, and birth size: a Mendelian randomization study using fatty acid desaturase variants

Bernard Jonathan Y.; Pan Hong; Aris Izzuddin M.; Moreno-Betancur Margarita; Soh Shu-E; Yap Fabian; Tan Kok Hian; Shek Lynette P.; Chong Yap-Seng; Gluckman Peter D.; Calder Philip C.; Godfrey Keith M.; Chong Mary Foong-Fong; Kramer Michael S.; Karnani Neerja; Lee Yung Seng

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Long-chain polyunsaturated fatty acids, gestation duration, and birth size: a Mendelian randomization study using fatty acid desaturase variants

机译：长链多不饱和脂肪酸，妊娠持续时间和出生尺寸：使用脂肪酸去饱和酶变体进行孟德尔随机化研究

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Background: In randomized trials, supplementation of n-3 (omega-3) long-chain polyunsaturated fatty acids (LC-PUFAs) during pregnancy has resulted in increased size at birth, which is attributable to longer gestation.

机译：背景：在随机试验中，妊娠期N-3（OMEGA-3）长链多不饱和脂肪酸（LC-PUFA）的补充导致出生时的大小增加，可归因于妊娠更长。

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来源
《The American Journal of Clinical Nutrition: Official Journal of the American Society for Clinical Nutrition》 |2018年第1期|共9页
作者
Bernard Jonathan Y.; Pan Hong; Aris Izzuddin M.; Moreno-Betancur Margarita; Soh Shu-E; Yap Fabian; Tan Kok Hian; Shek Lynette P.; Chong Yap-Seng; Gluckman Peter D.; Calder Philip C.; Godfrey Keith M.; Chong Mary Foong-Fong; Kramer Michael S.; Karnani Neerja; Lee Yung Seng;
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作者单位

ASTAR Singapore Inst Clin Sci Singapore Singapore;

ASTAR Singapore Inst Clin Sci Singapore Singapore;

ASTAR Singapore Inst Clin Sci Singapore Singapore;

Murdoch Childrens Res Inst Clin Epidemiol &

Biostat Unit Melbourne Vic Australia;

ASTAR Singapore Inst Clin Sci Singapore Singapore;

Kandang Kerbau Womens &

Childrens Hosp Dept Pediat Endocrinol Singapore Singapore;

Kandang Kerbau Womens &

Childrens Hosp Dept Maternal Fetal Med Singapore Singapore;

ASTAR Singapore Inst Clin Sci Singapore Singapore;

ASTAR Singapore Inst Clin Sci Singapore Singapore;

ASTAR Singapore Inst Clin Sci Singapore Singapore;

Univ Southampton Fac Med Southampton Hants England;

Univ Southampton Fac Med Southampton Hants England;

ASTAR Singapore Inst Clin Sci Singapore Singapore;

Yong Loo Lin Sch Med Dept Obstet &

Gynecol Singapore Singapore;

ASTAR Singapore Inst Clin Sci Singapore Singapore;

ASTAR Singapore Inst Clin Sci Singapore Singapore;

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原文格式 PDF
正文语种 eng
中图分类营养卫生、食品卫生;
关键词
pregnancy; birth size; fatty acids; cohort studies; Mendelian randomization;

机译：怀孕;出生尺寸;脂肪酸;队列研究;孟德尔随机化;

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专利

1. Long-chain polyunsaturated fatty acids, gestation duration, and birth size: a Mendelian randomization study using fatty acid desaturase variants [J] . Bernard Jonathan Y., Pan Hong, Aris Izzuddin M., The American Journal of Clinical Nutrition: Official Journal of the American Society for Clinical Nutrition . 2018,第1期

机译：长链多不饱和脂肪酸，妊娠持续时间和出生尺寸：使用脂肪酸去饱和酶变体进行孟德尔随机化研究
2. Genetic variants of the fatty acid desaturase gene cluster predict amounts of red blood cell docosahexaenoic and other polyunsaturated fatty acids in pregnant women: findings from the Avon Longitudinal Study of Parents and Children. [J] . Koletzko B, Lattka E, Zeilinger S, The American Journal of Clinical Nutrition: Official Journal of the American Society for Clinical Nutrition . 2011,第1期

机译：脂肪酸去饱和酶基因簇的遗传变异预测孕妇中红细胞二十二碳六烯酸和其他多不饱和脂肪酸的量：雅芳父母和儿童纵向研究的发现。
3. Biosynthesis of Polyunsaturated Fatty Acids in Octopus vulgaris : Molecular Cloning and Functional Characterisation of a Stearoyl-CoA Desaturase and an Elongation of Very Long-Chain Fatty Acid 4 Protein [J] . óscar Monroig, Rosa de Llanos, Inmaculada Varó, Marine Drugs . 2017,第3期

机译：章鱼的多不饱和脂肪酸的生物合成：硬脂酰辅酶A去饱和酶和非常长链脂肪酸4蛋白的延伸的分子克隆和功能表征。
4. Clinical Overview of Effects of Dietary Long-Chain Polyunsaturated Fatty Acids during the Perinatal Period [C] . Susan A. Scholtz, John Colombo, Susan E. Carlson Nestlé Nutrition Workshop . 2013

机译：季后期膳食长链多不饱和脂肪酸作用的临床概述
5. Litter birth weight phenotype and maternal n-3 long-chain polyunsaturated fatty acid supplementation in pigs. [D] . Smit, Miranda Nicolette. 2013

机译：仔猪出生体重表型和母体n-3长链多不饱和脂肪酸的补充。
6. Long-chain polyunsaturated fatty acids gestation duration and birth size: a Mendelian randomization study using FADS variants [O] . Jonathan Y. Bernard, Hong Pan, Izzuddin M. Aris, -1

机译：长链多不饱和脂肪酸妊娠持续时间和出生年龄：使用FADS变体的孟德尔随机研究
7. A randomised controlled trial investigating the effect of n-3 long-chain polyunsaturated fatty acid supplementation on cognitive and retinal function in cognitively healthy older people: the Older People And n-3 Long-chain polyunsaturated fatty acids (OPAL) study protocol ISRCTN72331636 [O] . Dangour Alan D, Clemens Felicity, Elbourne Diana, 2011

机译：一项随机对照试验，研究补充n-3长链多不饱和脂肪酸对认知健康的老年人的认知和视网膜功能的影响：老年人和n-3长链多不饱和脂肪酸（OPAL）研究方案ISRCTN72331636

Long-chain polyunsaturated fatty acids, gestation duration, and birth size: a Mendelian randomization study using fatty acid desaturase variants

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