The association of fatty acid desaturase gene polymorphisms on long-chain polyunsaturated fatty acid composition in Indonesian infants

Tanjung Conny; Rzehak Peter; Sudoyo Herawati; Mansyur Muchtaruddin; Munasir Zakiudin; Immanuel Suzanna; Irawan Roedi; Reischl Eva; Demmelmair Hans; Hadinegoro Sri Rezeki; Sjarif Damayanti Rusli; Koletzko Berthold

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The association of fatty acid desaturase gene polymorphisms on long-chain polyunsaturated fatty acid composition in Indonesian infants

机译：脂肪酸去饱和酶基因多态性对印度尼西亚婴幼儿长链多不饱和脂肪酸组成的缔合

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Background: Adequate availability of long-chain polyunsaturated fatty acids (LC-PUFAs) is important for human health from pregnancy to adulthood. Previous studies on fatty acid desaturase (FADS) gene single-nucleotide polymorphisms (SNPs) have been performed predominantly in Western populations and showed that FADS SNPs had a marked impact on LC-PUFA composition in blood and tissues.

机译：背景技术：长链多不饱和脂肪酸（LC-PUFA）的足够可用性对人类健康到成年期的人类健康是重要的。以前关于脂肪酸去饱和酶（FADS）基因单核苷酸多态性（SNP）的研究主要在西部群体中进行，并表明FADS SNP对血液和组织中的LC-PUFA组成具有显着的影响。

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来源
《The American Journal of Clinical Nutrition: Official Journal of the American Society for Clinical Nutrition》 |2018年第5期|共10页
作者
Tanjung Conny; Rzehak Peter; Sudoyo Herawati; Mansyur Muchtaruddin; Munasir Zakiudin; Immanuel Suzanna; Irawan Roedi; Reischl Eva; Demmelmair Hans; Hadinegoro Sri Rezeki; Sjarif Damayanti Rusli; Koletzko Berthold;
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作者单位

Pantai Indah Kapuk Hosp Jakarta Indonesia;

Univ Munich LMU Ludwig Maximilians Univ Munchen Dr Von Hauner Childrens Hosp Div Metab &

Nutr;

Univ Sydney Fac Med Sydney NSW Australia;

Univ Indonesia Fac Community Med Jakarta Indonesia;

Univ Indonesia Dr Ciptomangunkusumo Natl Referral Hosp Fac Med Dept Pediat Jakarta Indonesia;

Univ Indonesia Dr Ciptomangunkusumo Natl Referral Hosp Fac Med Dept Clin Pathol Jakarta;

Univ Airlangga Dr Sutomo Gen Hosp Fac Med Dept Pediat Surabaya Indonesia;

Helmholtz Zentrum Muenchen Inst Epidemiol 2 Res Unit Mol Epidemiol Munich Germany;

Univ Munich LMU Ludwig Maximilians Univ Munchen Dr Von Hauner Childrens Hosp Div Metab &

Nutr;

Univ Indonesia Dr Ciptomangunkusumo Natl Referral Hosp Fac Med Dept Pediat Jakarta Indonesia;

Indonesian Med Educ &

Res Inst Human Genet Jakarta Indonesia;

Univ Munich LMU Ludwig Maximilians Univ Munchen Dr Von Hauner Childrens Hosp Div Metab &

Nutr;

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原文格式 PDF
正文语种 eng
中图分类营养卫生、食品卫生;
关键词
FADS1; FADS2; FADS3; polymorphisms; fetus; LC-PUFA composition; Indonesia;

机译：FADS1;FADS2;FADS3;多态性;胎儿;LC-PUFA组成;印度尼西亚;

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专利

1. The association of fatty acid desaturase gene polymorphisms on long-chain polyunsaturated fatty acid composition in Indonesian infants [J] . Tanjung Conny, Rzehak Peter, Sudoyo Herawati, The American Journal of Clinical Nutrition: Official Journal of the American Society for Clinical Nutrition . 2018,第5期

机译：脂肪酸去饱和酶基因多态性对印度尼西亚婴幼儿长链多不饱和脂肪酸组成的缔合
2. Association of polyunsaturated fatty acids in breast milk with fatty acid desaturase gene polymorphisms among Chinese lactating mothers [J] . Ding Zhen, Liu Guo-Liang, Li Xiang, Prostaglandins, Leukotrienes, and Essential Fatty Acids . 2016,第Null期

机译：中国哺乳期母亲母乳中多不饱和脂肪酸与脂肪酸去饱和酶基因多态性的关系
3. Association analyses of single nucleotide polymorphisms in bovine stearoyl-CoA desaturase and fatty acid synthase genes with fatty acid composition in commercial cross-bred beef steers. [J] . Changxi Li Aldai N, Vinsky M, Dugan M. E. R, Animal Genetics . 2012,第1期

机译：商用杂种牛公牛中硬脂酰辅酶A去饱和酶和脂肪酸合酶基因单核苷酸多态性与脂肪酸组成的关联分析
4. Genetic association of delta-six fatty acid desaturase single nucleotide polymorphic molecular marker and muscle long chain omega-3 fatty acids in Australian lamb [C] . Malau-Aduli A.E.O., Bignell C.W., McCulloch R., ICoMST 2011;International conference of meat science and technology . 2012

机译：澳洲小羊三角洲六种脂肪酸脱氢酶单核苷酸多态性分子标记与肌肉长链omega-3脂肪酸的遗传关联
5. Long-chain polyunsaturated fatty acid intake and its relationship to red blood cell and plasma long-chain polyunsaturated fatty acids in women at high risk for breast cancer. [D] . Harvey, Katherine E. 2010

机译：罹患乳腺癌高风险女性的长链多不饱和脂肪酸摄入及其与红细胞和血浆长链多不饱和脂肪酸的关系。
6. The association of fatty acid desaturase gene polymorphisms on long-chain polyunsaturated fatty acid composition in Indonesian infants [O] . Conny Tanjung, Peter Rzehak, Herawati Sudoyo, -1

机译：印尼婴儿脂肪酸去饱和酶基因多态性与长链多不饱和脂肪酸组成的关系
7. Fatty acid desaturase (FADS) gene polymorphisms and insulin resistance in association with serum phospholipid polyunsaturated fatty acid composition in healthy Korean men: cross-sectional study [O] . Yang Long In, Lim Hyo Hee, Kim Oh Yoen, 2011

机译：朝鲜健康男性的脂肪酸去饱和酶（）基因多态性和胰岛素抵抗与血清磷脂多不饱和脂肪酸组成的关系

The association of fatty acid desaturase gene polymorphisms on long-chain polyunsaturated fatty acid composition in Indonesian infants

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