Hormone Receptors Analysis in Idiopathic Progressive Subglottic Stenosis

摘要

Objective: Idiopathic subglottic stenosis predominantly affects fertile and perimenopausal women. Estrogens and/or progesterone have been proposed as mediators of its pathogenesis by stimulating collagen deposition within the upper airway. We evaluated the presence and expression of estrogen-alpha (ER-alpha), estrogen-beta (ER-beta), and progesterone receptors (PR) in idiopathic stenotic patients.