Effect of Treat-to-target Strategies Aiming at Remission of Arterial Stiffness in Early Rheumatoid Arthritis: A Randomized Controlled Study

Tam Lydia Ho-Pui; Shang Qing; Li Edmund Kwok-Ming; Wong Priscilla Ching-Han; Kwok Kitty Yan; Kun Emily Wai-Lin; Yim Isaac Cheuk-Wan; Lee Violet Ka-Lai; Yip Ronald Man-Lung; Pang Steve Hin-Ting; Lao Virginia Weng-Nga; Mak Queenie Wah-Yan; Cheng Isaac Tsz-Ho; Lau Xerox Sze-Lok; Li Tena Ka-Yan; Zhu Tracy Yaner; Lee Alex Pui-Wai; Tam Lai-Shan

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Effect of Treat-to-target Strategies Aiming at Remission of Arterial Stiffness in Early Rheumatoid Arthritis: A Randomized Controlled Study

机译：治疗对目标策略旨在缓解早期类风湿性关节炎动脉僵硬度的影响：随机对照研究

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摘要

Objective. To determine the efficacy of 2 tight control treatment strategies aiming at Simplified Disease Activity Score (SDAI) remission (SDAI = 33) compared to 28-joint count Disease Activity Score (DAS28) remission (DAS28 2.6) in the prevention of arterial stiffness in patients with early rheumatoid arthritis (RA).

机译：客观的。为了确定针对28关节计数疾病活动评分（DAS28）缓解（DAS28）的28关节计数疾病活动评分（DAS28）缓解（DAS28）缓解（SDAI＆ 33）的2个紧控处理策略的疗效早期类风湿性关节炎（RA）患者的动脉僵硬。

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来源
《The Journal of rheumatology》 |2018年第9期|共11页
作者
Tam Lydia Ho-Pui; Shang Qing; Li Edmund Kwok-Ming; Wong Priscilla Ching-Han; Kwok Kitty Yan; Kun Emily Wai-Lin; Yim Isaac Cheuk-Wan; Lee Violet Ka-Lai; Yip Ronald Man-Lung; Pang Steve Hin-Ting; Lao Virginia Weng-Nga; Mak Queenie Wah-Yan; Cheng Isaac Tsz-Ho; Lau Xerox Sze-Lok; Li Tena Ka-Yan; Zhu Tracy Yaner; Lee Alex Pui-Wai; Tam Lai-Shan;
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作者单位

Chinese Univ Hong Kong Dept Med &

Therapeut Hong Kong Hong Kong Peoples R China;

Chinese Univ Hong Kong Dept Med &

Therapeut Hong Kong Hong Kong Peoples R China;

Chinese Univ Hong Kong Dept Med &

Therapeut Hong Kong Hong Kong Peoples R China;

Chinese Univ Hong Kong Dept Med &

Therapeut Hong Kong Hong Kong Peoples R China;

Queen Elizabeth Hosp Dept Med Hong Kong Hong Kong Peoples R China;

Tai Po Hosp Dept Med Hong Kong Hong Kong Peoples R China;

Tseung Kwan O Hosp Dept Med Hong Kong Hong Kong Peoples R China;

Pamela Youde Nethersole Eastern Hosp Dept Med Hong Kong Hong Kong Peoples R China;

Kwong Wah Hosp Dept Med Hong Kong Hong Kong Peoples R China;

Kwong Wah Hosp Dept Med Hong Kong Hong Kong Peoples R China;

Kwong Wah Hosp Dept Med Hong Kong Hong Kong Peoples R China;

Chinese Univ Hong Kong Dept Med &

Therapeut Hong Kong Hong Kong Peoples R China;

Chinese Univ Hong Kong Dept Med &

Therapeut Hong Kong Hong Kong Peoples R China;

Chinese Univ Hong Kong Dept Med &

Therapeut Hong Kong Hong Kong Peoples R China;

Chinese Univ Hong Kong Dept Med &

Therapeut Hong Kong Hong Kong Peoples R China;

Chinese Univ Hong Kong Dept Orthopaed &

Traumatol Hong Kong Hong Kong Peoples R China;

Chinese Univ Hong Kong Dept Med &

Therapeut Hong Kong Hong Kong Peoples R China;

Chinese Univ Hong Kong Dept Med &

Therapeut Hong Kong Hong Kong Peoples R China;

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原文格式 PDF
正文语种 eng
中图分类免疫性疾病;
关键词
EARLY RHEUMATOID ARTHRITIS; ARTERIAL STIFFNESS; PULSE WAVE VELOCITY; AUGMENTATION INDEX; REMISSION;

机译：早期类风湿性关节炎;动脉僵硬;脉搏波速度;增强指数;缓解;

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专利

1. Effect of Treat-to-target Strategies Aiming at Remission of Arterial Stiffness in Early Rheumatoid Arthritis: A Randomized Controlled Study [J] . Tam Lydia Ho-Pui, Shang Qing, Li Edmund Kwok-Ming, The Journal of rheumatology . 2018,第9期

机译：治疗对目标策略旨在缓解早期类风湿性关节炎动脉僵硬度的影响：随机对照研究
2. Adalimumab added to a treat-to-target strategy with methotrexate and intra-articular triamcinolone in early rheumatoid arthritis increased remission rates, function and quality of life. The OPERA Study: an investigator-initiated, randomised, double-blind, parallel-group, placebo-controlled trial. [J] . Kim H?rslev-Petersen, Merete Lund Hetland, Peter Junker, Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research . 2014,第4期

机译：阿达木单抗增加了甲氨蝶呤和关节内曲安奈德在类风湿关节炎中的靶向治疗策略，从而增加了缓解率，功能和生活质量。 OPERA研究：研究者发起的随机，双盲，平行组，安慰剂对照试验。
3. Adalimumab added to a treat-to-target strategy with methotrexate and intra-articular triamcinolone in early rheumatoid arthritis increased remission rates, function and quality of life. The OPERA Study: an investigator-initiated, randomised, double-blind, parallel-group, placebo-controlled trial. [J] . Kim H?rslev-Petersen, Merete Lund Hetland, Peter Junker, Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research . 2014,第4期

机译：阿达木单抗增加了甲氨蝶呤和关节内曲安奈德在类风湿关节炎中的靶向治疗策略，从而增加了缓解率，功能和生活质量。 OPERA研究：研究者发起的随机，双盲，平行组，安慰剂对照试验。
4. Effects of Short-Term Exposure to Fine and Ultrafine Particles from Indoor Sources on Arterial Stiffness - A Randomized Sham-Controlled Exposure Study of Healthy Volunteers [C] . Vanessa J. Soppa, Samir Shinnawi, Frauke Hennig, Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology . 2018

机译：短期暴露于室内细颗粒和超细颗粒对动脉僵硬度的影响-健康志愿者的随机假手术控制暴露研究
5. Vaccinia virus complement control protein ameliorates collagen induced arthritis: Potential implications for therapy of rheumatoid arthritis. [D] . Jha, Purushottam. 2003

机译：牛痘病毒补体控制蛋白可改善胶原蛋白诱发的关节炎：类风湿关节炎的治疗潜力。
6. Impact of a magnetic resonance imaging-guided treat-to-target strategy on disease activity and progression in patients with rheumatoid arthritis (the IMAGINE-RA trial): study protocol for a randomized controlled trial [O] . Signe Møller-Bisgaard, Kim Hørslev-Petersen, Bo Jannik Ejbjerg, 2015

机译：磁共振成像引导的靶向治疗策略对类风湿关节炎患者疾病活动和进展的影响（IMAGINE-RA试验）：一项随机对照试验的研究方案
7. Adalimumab added to a treat-to-target strategy with methotrexate and intra-articular triamcinolone in early rheumatoid arthritis increased remission rates, function and quality of life:The OPERA Study: an investigator-initiated, randomised, double-blind, parallel-group, placebo-controlled trial [O] . Horslev-Petersen Kim, Hetland M. L., Junker Peter, 2014

机译：阿达木单抗在甲类风湿关节炎中增加了甲氨蝶呤和关节内曲安奈德的靶向治疗策略，增加了缓解率，功能和生活质量：OPERA研究：研究者发起，随机，双盲，平行组，安慰剂对照试验

Effect of Treat-to-target Strategies Aiming at Remission of Arterial Stiffness in Early Rheumatoid Arthritis: A Randomized Controlled Study

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