Incidence of oral human papillomavirus infection

摘要

Aimee Kreimer and colleagues (Sept 7, p 877)1 report an annual incidence of oral human papillomavirus (HPV) infection of 4.4% in an international cohort of men (aged 18-73 years; n=l626; specimen collection every 6 months). We would like to offer a methodological explanation for the difference between this estimate and our estimate of 12-3% from a cohort in Seattle, WA, USA (aged 18-24 years; n=212; specimen collection every 4 months).There are several potential explanations, including differences in study population, sample size, and specimen collection schedule.