Treatment trends in early-stage lung cancer in the United States, 2004 to 2013: A time-trend analysis of the National Cancer Data Base

摘要

ObjectiveThe study objective was to evaluate trends in the use of surgical therapy for patients with early-stage (IA-IIA) non–small cell lung cancer when stereotactic ablative radiotherapy was introduced in the United States. MethodsPatients with clinical stage IA to IIA non–small cell lung cancer diagnosed from January 1, 2004, to December 31, 2013, were identified in the National Cancer Data Base. The Cochran–Armitage trend test was used to evaluate the change in the proportion of patients undergoing surgery over time. Logistic regression was used to identify the factors associated with receipt of surgery compared with radiation. ResultsOf 200,404 eligible patients from 1235 hospitals, 79.8% (n?=?159,943) underwent surgery. For all stages combined, the rate of surgery decreased from 83.9% in 2004 to 75.1% in 2013 (P?