Acquisition of Antibodies Against Endothelial Protein C Receptor-Binding Domains of Plasmodium falciparum Erythrocyte Membrane Protein 1 in Children with Severe Malaria

Rambhatla Janavi S.; Turner Louise; Manning Laurens; Laman Moses; Davis Timothy M. E.; Beeson James G.; Mueller Ivo; Warrel Jonathan; Theander Thor G.; Lavstsen Thomas; Rogerson Stephen J.

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Acquisition of Antibodies Against Endothelial Protein C Receptor-Binding Domains of Plasmodium falciparum Erythrocyte Membrane Protein 1 in Children with Severe Malaria

机译：在严重疟疾儿童中获取对疟原虫红细胞膜蛋白1的疟原虫红细胞膜蛋白1的内皮蛋白C受体结合结构域的抗体

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机译：背景

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来源
《The Journal of Infectious Diseases》 |2019年第5期|共11页
作者
Rambhatla Janavi S.; Turner Louise; Manning Laurens; Laman Moses; Davis Timothy M. E.; Beeson James G.; Mueller Ivo; Warrel Jonathan; Theander Thor G.; Lavstsen Thomas; Rogerson Stephen J.;
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作者单位

Univ Melbourne Peter Doherty Inst Infect &

Immun Dept Med Parkville Vic Australia;

Univ Copenhagen Fac Hlth &

Med Sci Dept Immunol &

Microbiol Ctr Med Parasitol Copenhagen;

Univ Western Australia Fiona Stanley Hosp Harry Perkins Res Inst Sch Med &

Pharmacol Murdoch;

Papua New Guinea Inst Med Res Madang Papua N Guinea;

Univ Western Australia Fiona Stanley Hosp Harry Perkins Res Inst Sch Med &

Pharmacol Murdoch;

Macfarlane Burnet Inst Med Res &

Publ Hlth Melbourne Vic Australia;

Univ Melbourne Dept Med Biol Parkville Vic Australia;

Papua New Guinea Inst Med Res Madang Papua N Guinea;

Univ Copenhagen Fac Hlth &

Med Sci Dept Immunol &

Microbiol Ctr Med Parasitol Copenhagen;

Univ Copenhagen Fac Hlth &

Med Sci Dept Immunol &

Microbiol Ctr Med Parasitol Copenhagen;

Univ Melbourne Peter Doherty Inst Infect &

Immun Dept Med Parkville Vic Australia;

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原文格式 PDF
正文语种 eng
中图分类传染病;
关键词
PfEMP1; Plasmodium falciparum; severe malaria; antibodies; Papua New Guinea; Luminex assay; CIDR; EPCR;

机译：pfemp1;疟原虫疟原虫;严重疟疾;抗体;巴布亚新几内亚;Luminex测定;CIDR;EPCR;

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专利

1. Acquisition of Antibodies Against Endothelial Protein C Receptor-Binding Domains of Plasmodium falciparum Erythrocyte Membrane Protein 1 in Children with Severe Malaria [J] . Rambhatla Janavi S., Turner Louise, Manning Laurens, The Journal of Infectious Diseases . 2019,第5期

机译：在严重疟疾儿童中获取对疟原虫红细胞膜蛋白1的疟原虫红细胞膜蛋白1的内皮蛋白C受体结合结构域的抗体
2. Acquisition of naturally acquired antibody response to Plasmodium falciparum erythrocyte membrane protein 1-DBLα and differential regulation of IgG subclasses in severe and uncomplicated malaria [J] . Natharinee Horata, Kiattawee Choowongkomon, Siriluk Ratanabunyong, 亚太热带生物医学杂志：英文版 . 2017,第012期

机译：在严重和不复杂的疟疾中获得对恶性疟原虫红细胞膜蛋白1-DBLα的自然获得性抗体应答和IgG亚类的差异调节
3. 3D7-Derived Plasmodium falciparum Erythrocyte Membrane Protein 1 Is a Frequent Target of Naturally Acquired Antibodies Recognizing Protein Domains in a Particular Pattern Independent of Malaria Transmission Intensity [J] . Louise Joergensen, Lasse S. Vestergaard, Louise Turner, The journal of immunology . 2007,第1期

机译：3D7来源的恶性疟原虫红细胞膜蛋白1是自然获得的抗体的常见目标，这些抗体以特定的模式识别蛋白结构域，而与疟疾的传播强度无关。
4. Antibodies to Malaria Peptide Mimics Inhibit Plasmodium falciparum Invasion of Erythrocytes [C] . J.L. Casey, A.M. Coley, J.K. Sabo, International Congress of Parasitology . 2006

机译：疟疾肽模拟物的抗体抑制疟原虫侵袭红细胞的侵袭
5. Development of a Viral Vaccine Vector Expressing a Plasmodium falciparum Erythrocyte Membrane Protein Domain to Target Severe Malaria [D] . Crager, Sara Eve 2011

机译：表达表达疟原虫红细胞膜蛋白结构膜蛋白域的病毒疫苗载体以靶向严重疟疾
6. IgG Antibodies to Endothelial Protein C Receptor-Binding Cysteine-Rich Interdomain Region Domains of Plasmodium falciparum Erythrocyte Membrane Protein 1 Are Acquired Early in Life in Individuals Exposed to Malaria [O] . Louise Turner, Thomas Lavstsen, Bruno P. Mmbando, 2015

机译：恶性疟原虫红细胞膜蛋白1的内皮蛋白C受体结合半胱氨酸丰富的域间域域域的IgG抗体是在感染疟疾的个体中早期获得的。
7. IgG Antibodies to Endothelial Protein C Receptor-Binding Cysteine-Rich Interdomain Region Domains of Plasmodium falciparum Erythrocyte Membrane Protein 1 Are Acquired Early in Life in Individuals Exposed to Malaria [O] . Louise Turner, Thomas Lavstsen, Bruno P. Mmbando, 2015

机译：IgG抗体对内皮蛋白C受体结合的半胱氨酸富含性疟原虫红细胞膜蛋白1的富含性域结构域在暴露于疟疾暴露于疟疾的个体的年初

Acquisition of Antibodies Against Endothelial Protein C Receptor-Binding Domains of Plasmodium falciparum Erythrocyte Membrane Protein 1 in Children with Severe Malaria

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