Saturated fatty acids, obesity, and the nucleotide oligomerization domain-like receptor protein 3 (NLRP3) inflammasome in asthmatic patients

Wood Lisa G.; Li Qian; Scott Hayley A.; Rutting Sandra; Berthon Bronwyn S.; Gibson Peter G.; Hansbro Philip M.; Williams Evan; Horvat Jay; Simpson Jodie L.; Young Paul; Oliver Brian G.; Baines Katherine J.

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Saturated fatty acids, obesity, and the nucleotide oligomerization domain-like receptor protein 3 (NLRP3) inflammasome in asthmatic patients

机译：饱和脂肪酸，肥胖和核苷酸寡聚化结构域样受体蛋白3（NLRP3）炎症在哮喘患者中

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Background: Both obesity and high dietary fat intake activate the nucleotide oligomerization domain-like receptor protein 3 (NLRP3) inflammasome.

机译：背景：肥胖症和高膳食脂肪摄入激活核苷酸寡聚域样受体蛋白3（NLRP3）炎症。

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来源
《The Journal of Allergy and Clinical Immunology》 |2019年第1期|共11页
作者
Wood Lisa G.; Li Qian; Scott Hayley A.; Rutting Sandra; Berthon Bronwyn S.; Gibson Peter G.; Hansbro Philip M.; Williams Evan; Horvat Jay; Simpson Jodie L.; Young Paul; Oliver Brian G.; Baines Katherine J.;
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作者单位

Univ Newcastle Prior Res Ctr Hlth Lungs Newcastle NSW Australia;

Univ Newcastle Prior Res Ctr Hlth Lungs Newcastle NSW Australia;

Univ Newcastle Prior Res Ctr Hlth Lungs Newcastle NSW Australia;

Univ Newcastle Prior Res Ctr Hlth Lungs Newcastle NSW Australia;

Univ Newcastle Prior Res Ctr Hlth Lungs Newcastle NSW Australia;

Univ Newcastle Prior Res Ctr Hlth Lungs Newcastle NSW Australia;

Univ Newcastle Prior Res Ctr Hlth Lungs Newcastle NSW Australia;

Univ Newcastle Prior Res Ctr Hlth Lungs Newcastle NSW Australia;

Univ Newcastle Prior Res Ctr Hlth Lungs Newcastle NSW Australia;

Univ Newcastle Prior Res Ctr Hlth Lungs Newcastle NSW Australia;

Woolcock Inst Med Res Sydney NSW Australia;

Woolcock Inst Med Res Sydney NSW Australia;

Univ Newcastle Prior Res Ctr Hlth Lungs Newcastle NSW Australia;

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原文格式 PDF
正文语种 eng
中图分类医学免疫学;
关键词
Fatty acids; saturated fat; obesity; inflammasome; airway inflammation; IL-1 beta; asthma;

机译：脂肪酸;饱和脂肪;肥胖;炎症;气道炎症;IL-1 beta;哮喘;

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专利

1. Saturated fatty acids, obesity, and the nucleotide oligomerization domain-like receptor protein 3 (NLRP3) inflammasome in asthmatic patients [J] . Wood Lisa G., Li Qian, Scott Hayley A., The Journal of Allergy and Clinical Immunology . 2019,第1期

机译：饱和脂肪酸，肥胖和核苷酸寡聚化结构域样受体蛋白3（NLRP3）炎症在哮喘患者中
2. Purinergic 2X7 Receptor is Involved in the Podocyte Damage of Obesity-Related Glomerulopathy via Activating Nucleotide-Binding and Oligomerization Domain-Like Receptor Protein 3 Inflammasome [J] . Xiao-Xia Hou, Hong-Rui Dong, Li-Jun Sun, 中华医学杂志（英文版） . 2018,第022期

机译：Purinergic 2X7受体通过激活核苷酸结合和寡聚化域样受体蛋白3炎症小体参与肥胖相关性肾病的足细胞损伤。
3. Nucleotide oligomerization domain-like receptor protein 1 inflammasome and vitiligo: progress in understanding the relationship [J] . Ren-He Chen1, Ru-Zhi Zhang1 国际皮肤性病学杂志(英文) . 2019,第001期

机译：核苷酸寡聚化域样受体蛋白1炎性小体和白癜风：了解关系的进展
4. INTERACTION OF FATTY ACID-BINDING PROTEINS WITH THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA [C] . Nathan M. Bass International Washington Spring Symposium . 1996

机译：脂肪酸结合蛋白与过氧化物体增殖物激活受体α的相互作用
5. Development of obesity-induced inflammation and insulin resistance: The role of adipose tissue, fatty acids, and Toll-like receptors. [D] . Davis, Jeremy E. 2008

机译：肥胖引起的炎症和胰岛素抵抗的发展：脂肪组织，脂肪酸和Toll样受体的作用。
6. Purinergic 2X7 Receptor is Involved in the Podocyte Damage of Obesity-Related Glomerulopathy via Activating Nucleotide-Binding and Oligomerization Domain-Like Receptor Protein 3 Inflammasome [O] . Xiao-Xia Hou, Hong-Rui Dong, Li-Jun Sun, 2018

机译：Purinergic 2X7受体通过激活核苷酸结合和寡聚化域样受体蛋白3炎症小体参与肥胖相关性肾病的足细胞损伤。
7. Empagliflozin Blunts Worsening Cardiac Dysfunction Associated With Reduced NLRP3 (Nucleotide-Binding Domain-Like Receptor Protein 3) Inflammasome Activation in Heart Failure [O] . Nikole J. Byrne, Nobutoshi Matsumura, Zaid H. Maayah, 2020

机译：Empagliflozin钝性恶化的心脏功能障碍与降低的NLRP3（核苷酸结合结构域样受体蛋白3）心力衰竭炎症组织活化

Saturated fatty acids, obesity, and the nucleotide oligomerization domain-like receptor protein 3 (NLRP3) inflammasome in asthmatic patients

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