The SQ tree SLIT-tablet is highly effective and well tolerated: Results from a randomized, double-blind, placebo-controlled phase III trial

Biedermann Tilo; Kuna Piotr; Panzner Petr; Valovirta Erkka; Andersson Morgan; de Blay Frederic; Thrane Dorthe; Jacobsen Sanja Hald; Stage Brian Sonne; Winther Lone

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The SQ tree SLIT-tablet is highly effective and well tolerated: Results from a randomized, double-blind, placebo-controlled phase III trial

机译：SQ树狭缝平板电脑具有高效且耐受性：随机，双盲，安慰剂对照期III试验结果

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Background: The SQ tree sublingual immunotherapy (SLIT)tablet (ALK-Abello, Horsholm, Denmark) is developed for treatment of tree pollen-induced allergic rhinoconjunctivitis (ARC).

机译：背景：SQ树舌下免疫疗法（缝隙）片剂（Alk-Abello，Horsholm，丹麦）是开发用于治疗树花粉诱导的过敏性鼻咽炎（ARC）。

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来源
《The Journal of Allergy and Clinical Immunology》 |2019年第3期|共15页
作者
Biedermann Tilo; Kuna Piotr; Panzner Petr; Valovirta Erkka; Andersson Morgan; de Blay Frederic; Thrane Dorthe; Jacobsen Sanja Hald; Stage Brian Sonne; Winther Lone;
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作者单位

Tech Univ Munich Dept Dermatol &

Allergol Biedersteiner Str 29 D-80802 Munich Germany;

Med Univ Lodz Barlicki Univ Hosp Div Internal Med Asthma &

Allergy Lodz Poland;

Charles Univ Prague Fac Med Pilsen Dept Immunol &

Allergol Prague Czech Republic;

Univ Turku Dept Pulm Dis &

Clin Allergol Turku Finland;

Skane Univ Hosp Dept Otorhinolaryngol Head &

Neck Surg Lund Sweden;

Univ Strasbourg Univ Hosp Strasbourg Federat Translat Med Chest Dis Dept Strasbourg France;

ALK Abello Global Clin Dev Horsholm Denmark;

ALK Abello Global Clin Dev Horsholm Denmark;

ALK Abello Global Clin Dev Horsholm Denmark;

Gentofte Univ Hosp Dept Dermato Allergol Allergy Clin Copenhagen Denmark;

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原文格式 PDF
正文语种 eng
中图分类医学免疫学;
关键词
Allergic rhinoconjunctivitis; allergy immunotherapy; birch pollen; clinical efficacy; clinical trial; safety; sublingual immunotherapy tablet; total combined score; tree pollen;

机译：过敏性鼻咽炎;过敏免疫疗法;桦树花粉;临床疗效;临床试验;安全;舌下免疫疗法平板电脑;总组合得分;树花粉;

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1. The SQ tree SLIT-tablet is highly effective and well tolerated: Results from a randomized, double-blind, placebo-controlled phase III trial [J] . Biedermann Tilo, Kuna Piotr, Panzner Petr, The Journal of Allergy and Clinical Immunology . 2019,第3期

机译：SQ树狭缝平板电脑具有高效且耐受性：随机，双盲，安慰剂对照期III试验结果
2. Efficacy of Thalidomide in Preventing Delayed Nausea and Vomiting Induced by Highly Emetogenic Chemotherapy: A Randomized, Multicenter, Double-Blind, Placebo-Controlled Phase III Trial (CLOG1302 study) [J] . Zhang Lingyun, Qu Xiujuan, Teng Yuee, Journal of Clinical Oncology . 2017,第31期

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5. A Phase II, Randomized, Double-Blind, Placebo-Controlled Trial of Fish Oil (Eicosapentaenoic Acid and Docosahexaenoic Acid) on Lung and Systemic Inflammation in Patients with Acute Lung Injury. [D] . Stapleton, Renee Doney. 2010

机译：鱼油（二十碳五烯酸和二十二碳六烯酸）对急性肺损伤患者的肺和全身炎症的II期，随机，双盲，安慰剂对照试验。
6. Osilodrostat Is an Effective and Well-Tolerated Treatment for Cushing’s Disease (CD): Results From a Phase III Study With an Upfront Randomized Double-Blind Placebo-Controlled Phase (LINC 4) [O] . Mônica Gadelha, Marie Bex, Richard A Feelders, 2021

机译：Osilodrostat是一种有效且耐受性耐受性的缓解疾病（CD）：由前期随机双盲安慰剂控制相（LINC 4）的研究结果。
7. Effective treatment of house dust mite–induced allergic rhinitis with 2 doses of the SQ HDM SLIT-tablet: Results from a randomized, double-blind, placebo-controlled phase III trial [O] . Demoly Pascal, Emminger Waltraud, Rehm Dorte, 2016

机译：服用2剂SQ HDM SLIT片剂可有效治疗屋尘螨引起的过敏性鼻炎：一项随机，双盲，安慰剂对照的III期临床试验的结果

The SQ tree SLIT-tablet is highly effective and well tolerated: Results from a randomized, double-blind, placebo-controlled phase III trial

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