Calcium deprivation markedly enhances guggulsterone accumulation in cell cultures of Commiphora wightii

摘要

Guggulsterone (Gs; two isomers -E and -Z, GsE and GsZ) is an effective anti-hyperlipidemic agent obtained from the gum resin of guggul tree, Commiphora wightii (Arnott.) Bhandari (syn. C. mukul). The recent reports explain the mechanism of its lipid lowering properties and its potential role in cancer therapy, making it an attractive molecule for production through biotechnological methods using this species.