NMR studies of a neurotoxin (candoxin) from Bungarus candidus - Presence of a predominantly beta-sheet structure

摘要

Complete sequence-specific H-1 resonance assignments of a neurotoxin, candoxin, from Bungarus candidus has been reported. Qualitative interpretation of the nOes, chemical shift indices and deuterium exchange rates indicate a highly ordered and rigid conformation for this protein with an extended conformation for more than 50% of the residues and the complete absence of alpha-helical segments. [References: 19]