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首页> 外文期刊>Current molecular medicine >Elevated Microsatellite Alterations at Selected Tetranucleotide Repeats (EMAST) and Microsatellite Instability in Patients with Colorectal Cancer and Its Clinical Features
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Elevated Microsatellite Alterations at Selected Tetranucleotide Repeats (EMAST) and Microsatellite Instability in Patients with Colorectal Cancer and Its Clinical Features

机译:大肠癌患者四核苷酸重复序列(EMAST)的微卫星改变升高和微卫星不稳定性及其临床特征

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Purpose: Recently, a different type of microsatellite instability (MSI) instability designated 'elevated microsatellite alterations at selected tetranucleotide repeats' (EMAST) has been reported in several neoplasms, but its clinical implications remain unclear. We aimed to determine the relationships among EMAST, MSI and clinicopathologic characteristics, including oncologic outcomes, in colorectal cancer (CRC).
机译:目的:最近,在一些肿瘤中已经报道了一种不同类型的微卫星不稳定性(MSI)不稳定性,称为“选定四核苷酸重复序列上的微卫星改变升高”(EMAST),但其临床意义尚不清楚。我们旨在确定结直肠癌(CRC)中EMAST,MSI与临床病理特征(包括肿瘤结局)之间的关系。

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