Plasma Mitochondrial DNA Levels as a Biomarker of Lipodystrophy Among HIV-Infected Patients Treated with Highly Active Antiretroviral Therapy (HAART)

摘要

Lipodystrophy is a common complication in HIV-infected patients taking highly active antiretroviral therapy. Its early diagnosis is crucial for timely modification of antiretroviral therapy. We hypothesize that mitochondrial DNA in plasma may be a potential marker of LD in HIV-infected individuals. In this study, we compared plasma mitochondrial DNA levels in HIV-infected individuals and non-HIV-infected individuals to investigate its potential diagnostic value.