An Update on Direct C-H Bond Functionalization of Nitrogen-Containing Fused Heterocycles

摘要

This report highlights the recent advances in direct C-H bond functionalization of 5,5- and 6,5-fused heterocycles containing at least two nitrogen atoms. Besides C-C bond formation, C-N, C-S, C-P, and C-Si bonds can also be created via a metal-catalyzed process. Some examples, where a C-H functionalization approach was applied for the synthesis of drug candidates, will be presented as well.