Preparation of Dialkyl l-(Alkylamino)alkylphosphonates, Alkyl (l-(Alkylamino)alkyl)phenylphosphinates and (l-(Alkylamino)alkyl)di-phenylphosphine Oxides via 'In Situ' Generated Iminium Ions

摘要

The reaction of trialkyl phosphites, dialkyl phenylphos-phonites or alkyl diphenylphosphinites with N-alkylalkanimines in the presence of hydrogen chloride gives dialkyl l-(alkylami-no)alkylphosphonates, alkyl [l-(alkylamino)alkyl]phenylphosphi-nates or [l-(alkylamino)alkyl]diphenylphosphine oxides respectively, via Arbusov-like reaction of iminium salts generated 'in situ' from N-alkylalkanimines. This reaction is an alternative and competitive to known method of preparation based on the addition of H-P compounds to N-alkylalkanimines, because it gives higher yields, no heating is necessary, and the isolation of products is easy.