Palladium-Catalyzed Intermolecular Heck-Type Dearomative [4+2] Annulation of 2H-Isoindole Derivatives with Internal Alkynes

摘要

Here, an interesting palladium-catalyzed intermolecular Heck-type dearomative [4 + 2] annulation of 2H-isoindole derivatives with internal alkynes has been developed, affording diverse polycyclic pyrrolidine scaffolds in good yield. This reaction is a useful method for the transformation of 2H-isoindole.