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Heat treatment effect on the mechanical properties, roughness and bone ingrowth capacity of 3D printing porous titanium alloy

机译:热处理对3D印刷多孔钛合金的力学性能,粗糙度和骨头发热能力

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摘要

The weak mechanical strength and biological inertia of Ti-6Al-4V porous titanium alloy limit its clinical application in the field of orthopedics. The present study investigated the influence of different solution temperatures (e.g. 800 degrees C, 950 degrees C and 1000 degrees C) on the mechanical properties, roughness and bone ingrowth capacity of Ti-6Al-4V porous titanium alloy prepared by Electron Beam Melting. It was found that the compressive and shear strength were promoted with the increase of solution temperature because of the transformed crystallinity of Ti-6Al-4V titanium alloy and phase changes from TiAl to TiAl + TiV. In addition, the topological morphology, surface roughness and wettability of the porous titanium alloy scaffolds were improved after heat treatment, and in turn, the adhesion rate and cell proliferation of bone marrow mesenchymal stem cells were enhanced. Compared with the scaffolds before and after heat treatment at 800 degrees C, the scaffolds heat-treated at 950 degrees C and 1000 degrees C achieved better bone ingrowth, extracellular matrix deposition and osseointegration. These findings indicate the great potential of heat treatment in possessing Ti-6Al-4V porous titanium alloy for orthopedic implant.
机译:Ti-6Al-4V多孔钛合金的弱机械强度和生物惯性限制其在骨科领域的临床应用。本研究研究了不同溶液温度(例如800℃,950℃和1000℃)对通过电子束熔化制备的Ti-6Al-4V多孔钛合金的机械性能,粗糙度和骨扩凝能力的影响。结果发现,由于Ti-6Al-4V钛合金的变化的结晶度和从TiAl + TiV的变化的变化,随着溶液温度的增加,促进了抗压和剪切强度。此外,热处理后多孔钛合金支架的拓扑形态,表面粗糙度和润湿性得到改善,又提高了骨髓间充质干细胞的粘合速率和细胞增殖。与800摄氏度的热处理前后的支架相比,在950℃和1000℃下热处理的支架实现了更好的骨骼,细胞外基质沉积和骨整合。这些发现表明具有用于整形外科植入物的Ti-6Al-4V多孔钛合金的热处理的巨大潜力。

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  • 来源
    《RSC Advances》 |2018年第22期|共13页
  • 作者单位

    Jilin Univ Hosp 2 Dept Orthoped Changchun 130041 Jilin Peoples R China;

    Cent S Univ Sch Mat Sci &

    Engn Changsha 410083 Hunan Peoples R China;

    Cent S Univ Sch Mat Sci &

    Engn Changsha 410083 Hunan Peoples R China;

    Jilin Univ Hosp 2 Dept Orthoped Changchun 130041 Jilin Peoples R China;

    Jilin Univ Hosp 2 Dept Orthoped Changchun 130041 Jilin Peoples R China;

    Jilin Univ Hosp 2 Dept Orthoped Changchun 130041 Jilin Peoples R China;

    Jilin Univ Hosp 2 Dept Orthoped Changchun 130041 Jilin Peoples R China;

    Jilin Univ Hosp 2 Dept Orthoped Changchun 130041 Jilin Peoples R China;

    Jilin Univ Hosp 2 Dept Orthoped Changchun 130041 Jilin Peoples R China;

    Jilin Univ Hosp 2 Dept Orthoped Changchun 130041 Jilin Peoples R China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 化学;
  • 关键词

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