Open-Label Single-Arm Phase II Trial of Sorafenib Therapy with Drug-eluting Bead Transarterial Chemoembolization in Patients with Unresectable Hepatocellular Carcinoma: Clinical Results

Cosgrove David P.; Reyes Diane K.; Pawlik Timothy M.; Feng Allen L.; Kamel Ihab R.; Geschwind Jean-Francois H.

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Open-Label Single-Arm Phase II Trial of Sorafenib Therapy with Drug-eluting Bead Transarterial Chemoembolization in Patients with Unresectable Hepatocellular Carcinoma: Clinical Results

机译：索拉非尼治疗的开放标签单臂期II试验用药物洗脱胎圈霉变化疗术治疗不可切除的肝细胞癌患者：临床结果

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Purpose: To determine the efficacy of combined continuous sorafenib therapy and drug-eluting bead (DEB) transarterial chemo-embolization (TACE) in patients with unresectable hepatocellular carcinoma (HCC).

机译：目的：确定连续索拉非尼治疗组合和药物洗脱珠（Deb）豆类蛋白栓塞（TACE）在不可切除的肝细胞癌（HCC）患者中的疗效。

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《Radiology 》 |2015年第2期| 共10页
作者
Cosgrove David P.; Reyes Diane K.; Pawlik Timothy M.; Feng Allen L.; Kamel Ihab R.; Geschwind Jean-Francois H.;
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Johns Hopkins Univ Sch Med Dept Med Oncol Baltimore MD 21287 USA;

Johns Hopkins Univ Sch Med Dept Intervent Radiol Baltimore MD 21287 USA;

Johns Hopkins Univ Sch Med Dept Surg Oncol Baltimore MD 21287 USA;

Johns Hopkins Univ Sch Med Dept Intervent Radiol Baltimore MD 21287 USA;

Johns Hopkins Univ Sch Med Dept Radiol Baltimore MD 21287 USA;

Johns Hopkins Univ Sch Med Dept Intervent Radiol Baltimore MD 21287 USA;

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正文语种 eng
中图分类放射医学 ;
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1. Open-Label Single-Arm Phase II Trial of Sorafenib Therapy with Drug-eluting Bead Transarterial Chemoembolization in Patients with Unresectable Hepatocellular Carcinoma: Clinical Results [J] . Cosgrove David P., Reyes Diane K., Pawlik Timothy M., Radiology . 2015 ,第2期

机译：索拉非尼疗法与药物洗脱小珠经动脉化学栓塞治疗无法切除的肝细胞癌的开放标签单臂II期临床试验：临床结果
2. Single-center phase II trial of transarterial chemoembolization with drug-eluting beads for patients with unresectable hepatocellular carcinoma: initial experience in the United States. [J] . Reyes DK, Vossen JA, Kamel IR, The cancer journal . 2009 ,第6期

机译：单中心II期经药物洗脱珠粒治疗难治性肝细胞癌的患者经动脉化疗栓塞的试验：在美国的初步经验。
3. Phase II trial of sorafenib combined with concurrent transarterial chemoembolization with drug-eluting beads for hepatocellular carcinoma. [J] . Pawlik TM, Reyes DK, Cosgrove D, Journal of Clinical Oncology . 2011 ,第30期

机译：索拉非尼联合并发经动脉化学栓塞与药物洗脱珠粒治疗肝细胞癌的II期临床试验。
4. Molecular Therapies in Hepatocellular Carcinoma beyond Sorafenib: Lessons from Failed Phase III Trials and Novel Targets [C] . Lipika Goyal, Andrew X. Zhu Gastrointestinal Cancers Symposium . 2014

机译：Sorafenib之外的肝细胞癌中的分子疗法：III期试验失败的课程和新型靶标
5. Sesquiterpene drugs as potential treatment for hepatocellular carcinoma (HCC): Preclinical evaluation of parthenolide administered via transarterial chemoembolization in a rat HCC tumor model. [D] . Chen, Zheng. 2016

机译：倍半萜类药物可作为肝细胞癌（HCC）的潜在治疗方法：在大鼠HCC肿瘤模型中，通过经动脉化学栓塞术施用的小白菊内酯的临床前评估。
6. Single-Center Phase II Trial of Transarterial Chemoembolization With Drug-Eluting Beads for Patients With Unresectable Hepatocellular Carcinoma [O] . Diane K. Reyes, Josephina A. Vossen, Ihab R. Kamel, -1

机译：用药物洗脱珠粒药物洗脱珠粒术治疗术治疗肝癌
7. Open-Label Single-Arm Phase II Trial of Sorafenib Therapy with Drug-eluting Bead Transarterial Chemoembolization in Patients with Unresectable Hepatocellular Carcinoma: Clinical Results [O] . David P. Cosgrove, Diane K. Reyes, Timothy M. Pawlik, 2015

机译：索拉非尼治疗的开放标签单臂期II试验用药物洗脱胎圈霉变化疗术治疗不可切除的肝细胞癌患者：临床结果

Open-Label Single-Arm Phase II Trial of Sorafenib Therapy with Drug-eluting Bead Transarterial Chemoembolization in Patients with Unresectable Hepatocellular Carcinoma: Clinical Results

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