The NADPH oxidase 4 protects vascular endothelial cells from copper oxide nanoparticles-induced oxidative stress and cell death

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The NADPH oxidase 4 protects vascular endothelial cells from copper oxide nanoparticles-induced oxidative stress and cell death

机译：NADPH氧化酶4保护来自氧化铜纳米粒子诱导的氧化应激和细胞死亡的血管内皮细胞

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Aims: Nanoparticles (NPs) exposure is associated with increased risk of cardiovascular diseases, but the underlying mechanism is still obscure. In this study, we investigated the role of NADPH oxidase 4 (NOX4) in copper oxide nanoparticles (CuONPs)-induced cytotoxicity in human umbilical vein endothelial cells (HUVECs).

机译：目的：纳米颗粒（NPS）暴露与心血管疾病的风险增加有关，但潜在的机制仍然模糊不清。在该研究中，我们研究了NADPH氧化酶4（NOX4）在氧化铜纳米粒子（CUONPS）中的作用 - 诱导人脐静脉内皮细胞（HUVECS）中的细胞毒性。

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《Life sciences》 |2020年第2020期|共7页
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正文语种 eng
中图分类医药、卫生;
关键词
CuONPs; Vascular endothelial cells (ECs); Downregulation of NOX4; Excessive accumulation of O-2(-); Oxidative stress and cell death;

机译：CuONPS;血管内皮细胞（ECS）;下调NOx4;O-2（ - ）的过度积累;氧化应激和细胞死亡;

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1. The NADPH oxidase 4 protects vascular endothelial cells from copper oxide nanoparticles-induced oxidative stress and cell death [J] . Life sciences . 2020,第期

机译：NADPH氧化酶4保护来自氧化铜纳米粒子诱导的氧化应激和细胞死亡的血管内皮细胞
2. Resveratrol protects vascular endothelial cells from high glucose-induced apoptosis through inhibition of nadph oxidase activation-driven oxidative stress [J] . ChenF., QianL.-H., DengB., CNS neuroscience & therapeutics . 2013,第9期

机译：白藜芦醇通过抑制nadph氧化酶激活驱动的氧化应激，保护血管内皮细胞免于高葡萄糖诱导的凋亡
3. Resveratrol Protects Vascular Endothelial Cells from High Glucose–Induced Apoptosis through Inhibition of NADPH Oxidase Activation–Driven Oxidative Stress [J] . Feng Chen, Li‐Hua Qian, Bo Deng, CNS neuroscience & therapeutics. . 2013,第9期

机译：白藜芦醇通过抑制NADPH氧化酶激活-驱动氧化应激，保护血管内皮细胞免于高糖诱导的细胞凋亡。
4. CHEMILUMINESCENCE STUDY ON THE REGULATION OF NADPH OXIDASE ACTIVITY BY THIOREDOXIN REDUCTASE IN VASCULAR ENDOTHELIAL CELLS [C] . XUN SHEN, ZHEN-BO LIU The 15th International Symposium on Bioluminescence and Chemilminescence(第十五届生物发光和化学发光国际会议)论文集 . 2008

机译：硫氧还蛋白还原酶调节血管内皮细胞对NADPH氧化酶活性的化学发光研究
5. Regulation of endothelial nitric oxide synthase by subcellular localization and NADPH oxidase. [D] . Zhang, Qian. 2007

机译：亚细胞定位和NADPH氧化酶对内皮型一氧化氮合酶的调节。
6. Resveratrol Protects Vascular Endothelial Cells from High Glucose–Induced Apoptosis through Inhibition of NADPH Oxidase Activation–Driven Oxidative Stress [O] . Feng Chen, Li‐Hua Qian, Bo Deng, 2013

机译：白藜芦醇通过抑制NADPH氧化酶激活-驱动氧化应激保护血管内皮细胞免于高糖诱导的细胞凋亡。
7. Resveratrol Protects Vascular Endothelial Cells from High Glucose-Induced Apoptosis through Inhibition of NADPH Oxidase Activation-Driven Oxidative Stress [O] . Feng Chen, Li-Hua Qian, Bo Deng, 2013

机译：通过抑制NADPH氧化酶活化驱动的氧化应激来保护来自高葡萄糖诱导的细胞凋亡的血管内皮细胞保护血管内皮细胞

The NADPH oxidase 4 protects vascular endothelial cells from copper oxide nanoparticles-induced oxidative stress and cell death

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