Asymmetrical cross-talk between the endoplasmic reticulum stress and oxidative stress caused by dextrose

摘要

Aims: Oxidative and endoplasmic reticulum (ER) stresses are implicated in premature cardiovascular disease in people with diabetes. The aim of the present study was to characterize the nature of the interplay between the oxidative and ER stresses to facilitate the development of therapeutic agents that can ameliorate these stresses.