Knockdown of ZBTB7A inhibits cell proliferation of breast cancer through regulating the ubiquitination of estrogen receptor alpha

Xiao Xiao; Shen Yingying; Yin Liyang; He Jun; Ni Xiaoyu; Luo Gang; Chen Xiguang; Zhu Wenbo; Zhong Jing; Liu Jianghua; Peng Xiuda; Zu Xuyu

首页> 外文期刊>Life sciences >Knockdown of ZBTB7A inhibits cell proliferation of breast cancer through regulating the ubiquitination of estrogen receptor alpha

【24h】

Knockdown of ZBTB7A inhibits cell proliferation of breast cancer through regulating the ubiquitination of estrogen receptor alpha

机译：通过调节雌激素受体α的泛素来抑制ZBTB7A的敲低抑制乳腺癌细胞增殖

获取原文

获取原文并翻译 | 示例

获取外文期刊封面封底 >>

开具论文收录证明 >>

文献代查 >>

团队文献服务 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Aims: ZBTB7A, a transcriptional repressor, accelerates the breast cancer progression. Over 70% of breast cancer samples are identified as ER-alpha positive. Due to the function of ZBTB7A in ER-alpha positive breast cancer incompletely known, we aimed to determine the role of ZBTB7A in ER-alpha positive cancer and explore the underlying mechanisms.

机译：目的：ZBTB7A，转录阻遏物，加速乳腺癌进展。超过70％的乳腺癌样品被鉴定为ER-α阳性。由于ZBTB7A在ER-α阳性乳腺癌中的功能不完全众所周知，我们旨在确定ZBTB7A在ER-α阳性癌症中的作用，并探讨潜在机制。

著录项

来源
《Life sciences 》 |2019年第2019期| 共8页
作者
Xiao Xiao; Shen Yingying; Yin Liyang; He Jun; Ni Xiaoyu; Luo Gang; Chen Xiguang; Zhu Wenbo; Zhong Jing; Liu Jianghua; Peng Xiuda; Zu Xuyu;
展开▼
作者单位

Univ South China Inst Clin Med Affiliated Hosp 1 69 Chuanshan Rd Hengyang 421001 Hunan;

Univ South China Inst Clin Med Affiliated Hosp 1 69 Chuanshan Rd Hengyang 421001 Hunan;

Univ South China Inst Clin Med Affiliated Hosp 1 69 Chuanshan Rd Hengyang 421001 Hunan;

Univ South China Dept Spine Surg Affiliated Nanhua Hosp Hengyang Hunan Peoples R China;

Univ South China Inst Clin Med Affiliated Hosp 1 69 Chuanshan Rd Hengyang 421001 Hunan;

Univ South China Inst Clin Med Affiliated Hosp 1 69 Chuanshan Rd Hengyang 421001 Hunan;

Univ South China Inst Clin Med Affiliated Hosp 1 69 Chuanshan Rd Hengyang 421001 Hunan;

Univ South China Inst Clin Med Affiliated Hosp 1 69 Chuanshan Rd Hengyang 421001 Hunan;

Univ South China Inst Clin Med Affiliated Hosp 1 69 Chuanshan Rd Hengyang 421001 Hunan;

Univ South China Inst Clin Med Affiliated Hosp 1 69 Chuanshan Rd Hengyang 421001 Hunan;

Univ South China Inst Clin Med Affiliated Hosp 1 69 Chuanshan Rd Hengyang 421001 Hunan;

Univ South China Inst Clin Med Affiliated Hosp 1 69 Chuanshan Rd Hengyang 421001 Hunan;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类医药、卫生 ;
关键词
ZBTB7A; Estrogen receptor alpha; Proteasomal degradation; Cell proliferation;

机译：ZBTB7A;雌激素受体α;蛋白酶体降解;细胞增殖;

相似文献

外文文献
中文文献
专利

1. Knockdown of ZBTB7A inhibits cell proliferation of breast cancer through regulating the ubiquitination of estrogen receptor alpha [J] . Xiao Xiao, Shen Yingying, Yin Liyang, Life sciences . 2019 ,第期

机译：通过调节雌激素受体α的泛素来抑制ZBTB7A的敲低抑制乳腺癌细胞增殖
2. Estrogen receptor alpha 46 is reduced in tamoxifen resistant breast cancer cells and re-expression inhibits cell proliferation and estrogen receptor alpha 66-regulated target gene transcription. [J] . Klinge CM, Riggs KA, Wickramasinghe NS, Molecular and Cellular Endocrinology . 2010 ,第2期

机译：在他莫昔芬耐药的乳腺癌细胞中雌激素受体α46降低，并且再表达抑制细胞增殖和雌激素受体α66调节的靶基因转录。
3. Myocardin Inhibits Estrogen Receptor Alpha-mediated Proliferation of Human Breast Cancer MCF-7 Cells via Regulating MicroRNA Expression [J] . Xiang Yuan, Lu Da-Lin, Li Jia-Peng, IUBMB life . 2016 ,第6期

机译：心肌素通过调节MicroRNA表达抑制雌激素受体α介导的人类乳腺癌MCF-7细胞增殖。
4. Assessing the phosphorylation status of estrogen receptor alpha isolated from human breast cancer cells [C] . David J. Britton, Birgit Schilling, Gary K. Scott, ASMS Conference on Mass Spectrometry and Allied Topics . 2007

机译：评估人乳腺癌细胞中雌激素受体α的磷酸化状态
5. SIRT1 represses estrogen-signaling, ligand-independent estrogen receptor alpha-mediated transcription, and cell proliferation in breast cancer cells via inhibition of the phosphoinositide 3-kinases pathway [D] . Moore, Robert L. 2011

机译：SIRT1通过抑制磷酸肌醇3激酶途径抑制雌激素信号传导，配体独立的雌激素受体α介导的转录和乳腺癌细胞的增殖
6. Estrogen receptor alpha 46 is reduced in tamoxifen resistant breast cancer cells and re-expression inhibits cell proliferation and estrogen receptor alpha 66-regulated target gene transcription [O] . Carolyn M. Klinge, Krista A. Riggs, Nalinie S. Wickramasinghe, -1

机译：雌激素受体α46在三莫氧基抗性乳腺癌细胞中降低再表达抑制细胞增殖和雌激素受体α66调节的靶基因转录
7. Estrogen receptor alpha 46 is reduced in tamoxifen resistant breast cancer cells and re-expression inhibits cell proliferation and estrogen receptor alpha 66-regulated target gene transcription [O] . Carolyn M. Klinge, Krista A. Riggs, Nalinie S. Wickramasinghe, 2010

机译：雌激素受体α46在三莫氧基抗性乳腺癌细胞中降低，再表达抑制细胞增殖和雌激素受体α66调节的靶基因转录
8. Membrane Estrogen Receptor Alpha Targeting and its Association with SHC in Regulating Breast Cancer Cell Proliferation [R] . Song, R. X. 2004

机译：膜雌激素受体α靶向及其与sHC调节乳腺癌细胞增殖的关系

Knockdown of ZBTB7A inhibits cell proliferation of breast cancer through regulating the ubiquitination of estrogen receptor alpha

摘要

著录项

相似文献

相关主题

期刊订阅