Electroacupuncture ameliorates cardiopulmonary bypass induced apoptosis in lung via ROS/Nrf2/NLRP3 inflammasome pathway

Dhar Rana; Zhang Lejun; Li Yajun; Rana Mohammad Nasiruddin; Hu Zhengqiang; Li Zigang; Cui Huashun; Tang Huifang

首页> 外文期刊>Life sciences >Electroacupuncture ameliorates cardiopulmonary bypass induced apoptosis in lung via ROS/Nrf2/NLRP3 inflammasome pathway

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Electroacupuncture ameliorates cardiopulmonary bypass induced apoptosis in lung via ROS/Nrf2/NLRP3 inflammasome pathway

机译：通过ROS / NRF2 / NLRP3炎症途径，电针改善了心肺旁路诱导肺细胞凋亡

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Aims: Electroacupuncture (EAc) has a pulmonary protective effect during cardiopulmonary bypass (CPB), but its molecular mechanisms including inflammasome activation signaling pathways remains unclear.

机译：目的：电针（EAC）在心肺旁路（CPB）期间具有肺保护作用，但其在包括炎症激活信号通路的分子机制仍不清楚。

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来源
《Life sciences》 |2019年第1期|共9页
作者
Dhar Rana; Zhang Lejun; Li Yajun; Rana Mohammad Nasiruddin; Hu Zhengqiang; Li Zigang; Cui Huashun; Tang Huifang;
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作者单位

Zhejiang Univ Sch Basic Med Sci Dept Pharmacol Hangzhou 310058 Zhejiang Peoples R China;

Zhejiang Univ Sch Basic Med Sci Dept Pharmacol Hangzhou 310058 Zhejiang Peoples R China;

Zhejiang Univ Sch Basic Med Sci Dept Pharmacol Hangzhou 310058 Zhejiang Peoples R China;

Zhejiang Univ Sch Basic Med Sci Dept Pharmacol Hangzhou 310058 Zhejiang Peoples R China;

Zhejiang Univ Sch Basic Med Sci Dept Pharmacol Hangzhou 310058 Zhejiang Peoples R China;

Zhejiang Univ Womens Hosp Sch Med Dept Anesthesiol Hangzhou 310003 Zhejiang Peoples R China;

Shanghai Univ Tradit Chinese Med Shuguang Hosp Dept Acupuncture Shanghai Peoples R China;

Zhejiang Univ Sch Basic Med Sci Dept Pharmacol Hangzhou 310058 Zhejiang Peoples R China;

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原文格式 PDF
正文语种 eng
中图分类医药、卫生;
关键词
Acupuncture; Cardiopulmonary bypass; Inflammasome; ROS; Apoptosis; Nrf2;

机译：针灸;心肺旁路;炎症;ROS;凋亡;NRF2;

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专利

1. Electroacupuncture ameliorates cardiopulmonary bypass induced apoptosis in lung via ROS/Nrf2/NLRP3 inflammasome pathway [J] . Dhar Rana, Zhang Lejun, Li Yajun, Life sciences . 2019,第1期

机译：通过ROS / NRF2 / NLRP3炎症途径，电针改善了心肺旁路诱导肺细胞凋亡
2. Diosmetin Alleviates Lipopolysaccharide-Induced Acute Lung Injury through Activating the Nrf2 Pathway and Inhibiting the NLRP3 Inflammasome [J] . Liu Qinmei, Ci Xinxin, Wen Zhongmei, Biomolecules & therapeutics . 2018,第2期

机译：Diosmetin通过激活NRF2途径来减轻脂多糖诱导的急性肺损伤并抑制NLRP3炎症
3. Electroacupuncture at ST-36 ameliorates DSS-induced acute colitis via regulating macrophage polarization induced by suppressing NLRP3/IL-1 beta and promoting Nrf2/HO-1 [J] . Song Shuangning, An Jing, Li Yingli, Molecular Immunology . 2019,第期

机译：通过抑制NLRP3 / IL-1β并促进NRF2 / HO-1，通过调节巨噬细胞偏振来改善DSS诱导的急性结肠炎的电机。
4. Neuroprotection of Glibenclamide against Brain Injury after Cardiac Arrest via Modulation of NLRP3 Inflammasome [C] . Xiuli Yang, Zhuoran Wang, Xiaofeng Jia Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2019

机译：格列本脲通过调节NLRP3炎症小体对心脏骤停后脑损伤的神经保护作用。
5. Lysosomal destabilization in retinal pigment epithelial cells activates the NLRP3 inflammasome and induces IL-1beta secretion. [D] . Tseng, Wen Allen. 2014

机译：视网膜色素上皮细胞中的溶酶体去稳定化激活NLRP3炎性小体并诱导IL-1β分泌。
6. Diosmetin Alleviates Lipopolysaccharide-Induced Acute Lung Injury through Activating the Nrf2 Pathway and Inhibiting the NLRP3 Inflammasome [O] . Qinmei Liu, Xinxin Ci, Zhongmei Wen, 2018

机译：薯os皂素通过激活Nrf2途径和抑制NLRP3炎性体减轻脂多糖诱导的急性肺损伤。
7. Melatonin Attenuates LPS-Induced Acute Depressive-Like Behaviors and Microglial NLRP3 Inflammasome Activation Through the SIRT1/Nrf2 Pathway [O] . Burak I. Arioz, Bora Tastan, Emre Tarakcioglu, 2019

机译：褪黑激素通过SIRT1 / NRF2途径衰减LPS诱导的急性抑郁样行为和微胶质NLRP3炎症活化

Electroacupuncture ameliorates cardiopulmonary bypass induced apoptosis in lung via ROS/Nrf2/NLRP3 inflammasome pathway

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