The novel diterpene 7 beta-acetoxy-20-hydroxy-19,20-epoxyroyleanone from Salvia corrugata shows complex cytotoxic activities against human breast epithelial cells

Cortese Katia; Marconi Silvia; DAlesio Carolina; Calzia Daniela; Panfoli Isabella; Tavella Sara; Aiello Cinzia; Pedrelli Francesca; Bisio Angela; Castagnola Patrizio

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The novel diterpene 7 beta-acetoxy-20-hydroxy-19,20-epoxyroyleanone from Salvia corrugata shows complex cytotoxic activities against human breast epithelial cells

机译：来自Salvia Corrugata的新型二萜7β-乙酰氧基-20-羟基-19,20-环氧基，显示出对人乳腺上皮细胞的复杂细胞毒性活性

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Aims: The aim of this study was the characterization of the in vitro cytotoxic properties of a recently isolated diterpene compound, 7 beta-acetoxy-20-hydroxy-19,20-epoxyroyleanone (compound 1), extracted from Salvia corrugata, versus human cell lines.

机译：目的：本研究的目的是从Salvia Corrugata，与人细胞提取的最近分离的二萜化合物，7β-乙酰氧基-20-羟基-19,20-环氧树脂（化合物1）的体外细胞毒性的表征。线条。

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来源
《Life sciences》 |2019年第2019期|共9页
作者
Cortese Katia; Marconi Silvia; DAlesio Carolina; Calzia Daniela; Panfoli Isabella; Tavella Sara; Aiello Cinzia; Pedrelli Francesca; Bisio Angela; Castagnola Patrizio;
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作者单位

Univ Genoa Dept Expt Med Human Anat DIMES Genoa Italy;

Univ Genoa Dept Expt Med Human Anat DIMES Genoa Italy;

Univ Genoa Dept Internal Med &

Med Specialties DiMI Genoa Italy;

Univ Genoa Dept Pharm DIFAR Genoa Italy;

Univ Genoa Dept Pharm DIFAR Genoa Italy;

Univ Genoa Dept Expt Med Human Anat DIMES Genoa Italy;

IRCCS Osped Policlin San Martino Dept Integrated Oncol Therapies Genoa Italy;

Univ Genoa Dept Pharm DIFAR Genoa Italy;

Univ Genoa Dept Pharm DIFAR Genoa Italy;

IRCCS Osped Policlin San Martino Dept Integrated Oncol Therapies Genoa Italy;

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原文格式 PDF
正文语种 eng
中图分类医药、卫生;
关键词
Diterpenes; Breast; ERBB2; Mitochondria; ERK1/2; ROS;

机译：diterpenes;乳房;erbb2;线粒体;erk1 / 2;ros;
入库时间 2022-08-19 17:42:27

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1. The novel diterpene 7 beta-acetoxy-20-hydroxy-19,20-epoxyroyleanone from Salvia corrugata shows complex cytotoxic activities against human breast epithelial cells [J] . Cortese Katia, Marconi Silvia, DAlesio Carolina, Life sciences . 2019,第期

机译：来自Salvia Corrugata的新型二萜7β-乙酰氧基-20-羟基-19,20-环氧基，显示出对人乳腺上皮细胞的复杂细胞毒性活性
2. New macrocyclic diterpenes from Euphorbia connata Boiss. with cytotoxic activities on human breast cancer cell lines [J] . Shadi Somayeh, Saeidi Hojjatollah, Ghanadian Mustafa, Natural product research . 2015,第7a9期

机译：来自大戟属Boiss的新的大环二萜。对人乳腺癌细胞系具有细胞毒活性
3. Improvement of cytotoxic activity of local anesthetics against human breast cancer cell line through the cyclodextrin complexes [J] . Sabari Chandrabose Leela, Sivakumar Krishnamoorthy, Rajamohan Rajaram Journal of Macromolecular Science. Pure and Applied Chemistry . 2017,第1a6期

机译：通过环糊精复合物改善局部麻醉剂对人乳腺癌细胞系的细胞毒性活性
4. Differential Uptake of PEG-Silica-FITC Nanoparticles by Human Breast Cancer Cells and Normal Human Breast Epithelial Cells [C] . N. Iwakuma, P. Sharma, M. J. Delano, Nano Science and Technology Institute(NSTI) Nanotechnology Conference and Trade Show(NSTI Nanotech 2007) vol.2; 20070520-24; Santa Clara,CA(US) . 2007

机译：人乳腺癌细胞和正常人乳腺癌上皮细胞对PEG-Silica-FITC纳米颗粒的摄取差异
5. Polychlorinated biphenyl (PCB)-induced oxidative stress mediates cytotoxicity in human breast and prostate epithelial cells [D] . Zhu, Yueming 2011

机译：多氯联苯（PCB）诱导的氧化应激介导人乳腺和前列腺上皮细胞的细胞毒性
6. Manool a Salvia officinalis diterpene induces selective cytotoxicity in cancer cells [O] . Pollyanna Francielli de Oliveira, Carla Carolina Munari, Heloiza Diniz Nicolella, 2016

机译：甘草丹参二萜诱导癌细胞的选择性细胞毒性
7. Cytotoxic activity of the chloroform extract and four diterpenes isolated from Salvia ballotiflora [O] . Nimsi Campos-Xolalpa, Ángel Josabad Alonso-Castro, Ernesto Sánchez-Mendoza, 2017

机译：从salvia ballotiflora分离的氯仿提取物和四种二萜的细胞毒活性

The novel diterpene 7 beta-acetoxy-20-hydroxy-19,20-epoxyroyleanone from Salvia corrugata shows complex cytotoxic activities against human breast epithelial cells

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