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Multifunctional fluorescent carbon dots inhibit the invasiveness of lung cancer cells

机译:多功能荧光碳点抑制肺癌细胞的侵袭性

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摘要

A new type of carbon dot (CD) is proposed, which has great potential to be an excellent fluorescent probe for bioimaging in vivo. Additionally, CDs can suppress the proliferation, migration and invasion of lung cancer cells by downregulating the protein expression of matrix metalloproteinase-2/9 and the activity of MMP-2.
机译:提出了一种新型的碳点(CD),其具有很大的潜力,可以是体内生物成像的优异荧光探针。 另外,CD通过下调基质金属蛋白酶-2 / 9的蛋白质表达和MMP-2的活性来抑制肺癌细胞的增殖,迁移和侵袭。

著录项

  • 来源
    《New Journal of Chemistry》 |2018年第18期|共4页
  • 作者单位

    Chongqing Univ Sch Pharmaceut Sci Chongqing 401331 Peoples R China;

    Army Med Univ Daping Hosp Inst Surg Res Dept Thorac Surg Chongqing 400042 Peoples R China;

    East China Univ Technol Sch Chem Biol &

    Mat Sci Nanchang 330013 Jiangxi Peoples R China;

    Chongqing Univ Sch Pharmaceut Sci Chongqing 401331 Peoples R China;

    Chongqing Normal Univ Coll Chem Chongqing Key Lab Green Synth &

    Applicat Chongqing 401331 Peoples R China;

    Chongqing Univ Sch Pharmaceut Sci Chongqing 401331 Peoples R China;

    Army Med Univ Daping Hosp Inst Surg Res Dept Thorac Surg Chongqing 400042 Peoples R China;

    Chongqing Univ Sch Pharmaceut Sci Chongqing 401331 Peoples R China;

    Southwest Univ Key Lab Luminescent &

    Real Time Analyt Chem Minist Educ Chongqing 400716 Peoples R China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 化学;
  • 关键词

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