Impact of NOD2/CARD15 polymorphisms on response to monoclonal antibody therapy in Crohn's disease: a systematic review and meta-analysis

Wang Xiaolei; Qin Li; Cao Jingli; Zhao Jing

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Impact of NOD2/CARD15 polymorphisms on response to monoclonal antibody therapy in Crohn's disease: a systematic review and meta-analysis

机译：NOD2 / CARD15基因多态性对克罗恩病单克隆抗体治疗反应的影响：系统评价和荟萃分析

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Objective: Crohn's disease (CD) is frequently treated with anti-tumor necrosis factor (TNF) monoclonal antibodies, and NOD2/CARD15 polymorphisms have been reported to predict treatment response. The purpose of this study was to perform a meta-analysis to determine the effect of NOD2/CARD15 polymorphisms on treatment response in patients with CD.

机译：目的：克罗恩病（CD）经常用抗肿瘤坏死因子（TNF）单克隆抗体治疗，并且据报道NOD2 / CARD15多态性可预测治疗反应。这项研究的目的是进行荟萃分析，以确定NOD2 / CARD15多态性对CD患者治疗反应的影响。

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《Current medical research and opinion 》 |2016年第12期| 共6页
作者
Wang Xiaolei; Qin Li; Cao Jingli; Zhao Jing;
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原文格式 PDF
正文语种 eng
中图分类医药、卫生 ;
关键词
CARD14; Crohn's disease; NOD2; Monoclonal; Polymorphism;

机译：CARD14;克罗恩病;NOD2;单克隆;多态性;

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1. Impact of NOD2/CARD15 polymorphisms on response to monoclonal antibody therapy in Crohn's disease: a systematic review and meta-analysis [J] . Wang Xiaolei, Qin Li, Cao Jingli, Current medical research and opinion . 2016 ,第12期

机译：NOD2 / CARD15基因多态性对克罗恩病单克隆抗体治疗反应的影响：系统评价和荟萃分析
2. Germline polymorphisms as biomarkers of tumor response in colorectal cancer patients treated with anti-EGFR monoclonal antibodies: a systematic review and meta-analysis [J] . Morgen E. K., Lenz H-J, Jonker D. J., The pharmacogenomics journal . 2017 ,第6期

机译：用抗EGFR单克隆抗体治疗的结肠直肠癌患者肿瘤反应的生物标志物：系统评价和荟萃分析
3. Monoclonal antibody therapy for Kawasaki disease: a protocol for systematic reviews and meta-analysis [J] . Osamu Nomura, Sayaka Fukuda, Erika Ota, Systematic Reviews . 2016 ,第1期

机译：川崎病的单克隆抗体疗法：系统评价和荟萃分析的方案
4. Association of CYP2D6 and ADRB1 Single Nucleotide Polymorphisms and Response to Beta Blocker Therapy in a Patient Sample Set with Cardiovascular Diseases from Romania [C] . Andrada Camelia Guta, Liana Gabriela Gruescu Molecular Medicine TRI-CON. . 2014

机译：CYP2D6和ADRB1单核苷酸多态性和对患者样本中β受体疗法的响应与来自罗马尼亚的心血管疾病
5. Yoga as an adjunctive therapy for Crohn's disease: A review of the effects of exercise and stress reduction on the quality of life and disease progression in Crohn's disease patients. [D] . Zuckerman, Julie. 2012

机译：瑜伽作为克罗恩氏病的辅助疗法：运动和减轻压力对克罗恩氏病患者生活质量和疾病进展的影响综述。
6. Monoclonal antibody therapy for Kawasaki disease: a protocol for systematic reviews and meta-analysis [O] . Osamu Nomura, Sayaka Fukuda, Erika Ota, 2016

机译：川崎病的单克隆抗体疗法：系统评价和荟萃分析的方案
7. P002 SERO-REACTIVITY TO MICROBIAL COMPONENTS IN CROHN'S DISEASE IS ASSOCIATED WITH ILEAL INVOLVEMENT, NON-INFLAMMATORY DISEASE BEHAVIOUR AND NOD2/CARD15 GENOTYPE, BUT NOT RESPONSE TO MEDICAL THERAPY OR RISK FOR SURGERY [O] . M. Papp, I. Altorjay, G.L. Norman, 2007

机译：P002对克罗恩病中微生物组分的血清反应性与髂骨受累，非炎症性疾病行为和Nod2 / Card15基因型相关，但对医疗治疗或手术风险的反应

Impact of NOD2/CARD15 polymorphisms on response to monoclonal antibody therapy in Crohn's disease: a systematic review and meta-analysis

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