机译:Ouabain抑制了胶质瘤U-87mg细胞的生长和迁移能力,通过抑制AKT / MTOR信号通路,下调HIF-1的表达
Logist Univ PAP Tianjin Key Lab Neurotrauma Repair Chinese Peoples Armed Police Force Ctr Neurol;
Logist Univ PAP Cent Lab Tianjin 300309 Peoples R China;
Logist Univ PAP Tianjin Key Lab Neurotrauma Repair Chinese Peoples Armed Police Force Ctr Neurol;
Logist Univ PAP Tianjin Key Lab Biomarkers Occupat &
Environm Haz Tianjin 300309 Peoples R China;
Logist Univ PAP Tianjin Key Lab Neurotrauma Repair Chinese Peoples Armed Police Force Ctr Neurol;
Logist Univ PAP Tianjin Key Lab Neurotrauma Repair Chinese Peoples Armed Police Force Ctr Neurol;
Logist Univ PAP Tianjin Key Lab Neurotrauma Repair Chinese Peoples Armed Police Force Ctr Neurol;
Logist Univ PAP Tianjin Key Lab Neurotrauma Repair Chinese Peoples Armed Police Force Ctr Neurol;
Logist Univ PAP Tianjin Key Lab Neurotrauma Repair Chinese Peoples Armed Police Force Ctr Neurol;
Logist Univ PAP Tianjin Key Lab Neurotrauma Repair Chinese Peoples Armed Police Force Ctr Neurol;
Logist Univ PAP Tianjin Key Lab Neurotrauma Repair Chinese Peoples Armed Police Force Ctr Neurol;
Logist Univ PAP Tianjin Key Lab Neurotrauma Repair Chinese Peoples Armed Police Force Ctr Neurol;
ouabain; glioblastoma; U-87MG cells; Akt; mammalian target of rapamycin signaling pathway; hypoxia-inducible factor-1;
机译:Ouabain抑制了胶质瘤U-87mg细胞的生长和迁移能力,通过抑制AKT / MTOR信号通路,下调HIF-1的表达
机译:Mahanine诱导细胞凋亡,细胞周期停滞,抑制胶质瘤细胞中细胞迁移,侵袭和PI3K / AKT / mTOR信号传导途径,并抑制体内肿瘤生长
机译:质子泵抑制剂通过下调V-ATPases / PI3K / Akt / mTOR /HIF-1α信号通路通过TSC1 / 2复合物和Rheb逆转人胃腺癌细胞中
多药耐药性的作用体内
机译:阳离子聚苯乙烯纳米球通过抑制Akt / mTOR和激活巨噬细胞和上皮细胞中的AMPK信号通路来诱导自噬
机译:多靶点受体酪氨酸激酶抑制剂利尼法尼(ABT-869)通过磷酸肌醇3激酶(PI3K)/ AKT依赖性信号传导途径诱导凋亡并抑制白血病细胞的增殖。
机译:哇巴因通过抑制Akt / mTOR信号通路和下调HIF-1α的表达来抑制神经胶质瘤U-87MG细胞的生长和迁移能力。
机译:M2通过PI3K / AKT / MTOR信号通路抑制胶质瘤中细胞迁移和侵袭的巨噬细胞衍生和侵袭