On the impact of smoothing and noise on robustness of CT and CBCT radiomics features for patients with head and neck cancers

摘要

Purpose: We investigated the characteristics of radiomics features extracted from planning CT (pCT) and cone beam CT (CBCT) image datasets acquired for 18 oropharyngeal cancer patients treated with fractionated radiation therapy. Images were subjected to smoothing, sharpening, and noise to evaluate changes in features relative to baseline datasets.