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TH‐AB‐BRA‐01: A Novel Doubly‐Focused Multileaf Collimator Design for MR‐Guided Radiation Therapy

机译:Th-AB-BRA-01:一种新型的双重聚焦多叶准直器设计,用于MR-Buided放射治疗

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Purpose: To describe the physical and dosimetric properties of a novel double‐stack multileaf collimator (MLC). Methods: One of the compromises made in the MLC design has been to employ linear‐motion singly‐divergent shapes. Because the MLC leading edge moves linearly, it is rounded to provide a consistent, albeit compromised penumbra. The MLC employed in the new linac‐based MR‐IGRT unit is designed to be doubly focused in that each leaf moves in an arc centered at the source, and the sides of the leaves are machined such that they lie parallel to a line between the leaf edge and the source. The curvature of the MLC keeps motors and encoders in lower magnetic field. However, high spatial‐resolution leaves are difficult to manufacture to sufficiently tight tolerances and difficult to move due to restricted space on the gantry. Wider leaves alleviate this problem with less moving parts but the coarse resolution disallows treating very small lesions. This compromise has been overcome by splitting the MLC leaf bank into two sets, stacked one upon the other and offset half of a leaf width. The dosimetry has been simulated using Monte‐Carlo and a 6 MV linac in a 0.35 T magnetic field. Results: The combined MLC leaf set has a spatial resolution of effectively half of the leaf width, 4mm here. The dosimetry resolution and conformality are consistent with 4mm wide MLC assisted by inverse fluence modulation. Also, because each leaf junction is backed up by the stacked leaf that lies over the junction, the problem of tongue‐and‐groove dosimetry has been greatly reduced. The novel MLC design allows the use of more powerful leaf motors than would be otherwise possible if a single MLC bank is employed. Conclusions: The stacked MLC will provide highly conformal dose distributions suitable for stereotactic radiation therapy of small lesions. The research was funded by ViewRay, Inc.
机译:目的:描述新型双层堆叠多叶准直器(MLC)的物理和剂量性质。方法:MLC设计中制造的折衷之一是采用线性运动单分歧形状。因为MLC前沿线性移动,所以它是四舍五入的,以提供一致的,尽管妥协的Penumbra。基于新的LINAC的MR-IGRT单元中采用的MLC被设计成双重聚焦,因为每个叶片在源处的弧形中移动,并且叶子的侧面被加工,使得它们平行于圆形叶边缘和源。 MLC的曲率使电动机和编码器保持在较低磁场中。然而,高空间分辨率的叶子难以制造足够紧的公差并且由于龙门上的限制空间而难以移动。更宽的叶子通过更少的移动部件来缓解这个问题,但粗糙分辨率易于治疗非常小的病变。通过将MLC叶片堤岸分成两组,堆叠在叶片宽度的另一个和偏移的一半上,已经克服了这种折衷。使用Monte-Carlo和0.35 T磁场中的6 MV LinAc模拟了剂量测定。结果:合并的MLC叶片套装具有有效的叶片宽度的空间分辨率,在此4毫米。剂量分辨率和依次性与4mm宽的MLC一致,通过逆用调制辅助。而且,因为每个叶片连接用位于结束的堆叠叶上,所以大大减少了舌沟剂量的问题。新颖的MLC设计允许使用比采用单一MLC银行的更强大的叶电机,而不是其他可能的叶电机。结论:堆叠的MLC将提供适用于小病变的立体定向辐射治疗的高度保形剂量分布。该研究由Viewray,Inc。提供资金

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