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The lncLocator: a subcellular localization predictor for long non-coding RNAs based on a stacked ensemble classifier

机译:LNClocator:基于堆叠的集合分类器的长非编码RNA的亚细胞定位预测器

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摘要

Motivation: The long non-coding RNA (lncRNA) studies have been hot topics in the field of RNA biology. Recent studies have shown that their subcellular localizations carry important information for understanding their complex biological functions. Considering the costly and time-consuming experiments for identifying subcellular localization of lncRNAs, computational methods are urgently desired. However, to the best of our knowledge, there are no computational tools for predicting the lncRNA subcellular locations to date.
机译:动机:长期非编码RNA(LNCRNA)研究是RNA生物学领域的热门话题。 最近的研究表明,他们的亚细胞本地化为理解其复杂的生物学功能提供重要信息。 考虑到识别LNCRNA的亚粒定位的昂贵和耗时的实验,迫切需要计算方法。 然而,据我们所知,迄今为止无法预测LNCRNA亚细胞位置的计算工具。

著录项

  • 来源
    《Bioinformatics》 |2018年第13期|共10页
  • 作者单位

    Shanghai Jiao Tong Univ Inst Image Proc &

    Pattern Recognit Shanghai 200240 Peoples R China;

    Erasmus MC Dept Med Informat NL-3014 ZK Rotterdam Netherlands;

    Shanghai Jiao Tong Univ Dept Comp Sci Shanghai 200240 Peoples R China;

    Chinese Acad Sci Shanghai Inst Tech Phys State Key Lab Infrared Phys Shanghai 200083 Peoples R China;

    Shanghai Jiao Tong Univ Inst Image Proc &

    Pattern Recognit Shanghai 200240 Peoples R China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 生物工程学(生物技术);
  • 关键词

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