Reactome diagram viewer: data structures and strategies to boost performance

摘要

Motivation: Reactome is a free, open-source, open-data, curated and peer-reviewed knowledge-base of biomolecular pathways. For web-based pathway visualization, Reactome uses a custom pathway diagram viewer that has been evolved over the past years. Here, we present comprehensive enhancements in usability and performance based on extensive usability testing sessions and technology developments, aiming to optimize the viewer towards the needs of the community.